Results 1 to 10 of about 12,742 (207)
Synthesis of Porphyrin and Bacteriochlorin Glycoconjugates through CuAAC Reaction Tuning. [PDF]
European J Org Chem, 2019 Rapid and reproducible access to a series of unique porphyrin and bacteriochlorin glycoconjugates, including meso‐glycosylated porphyrins and bacteriochlorins, and beta‐glycosylated porphyrins, using copper‐catalyzed azide–alkyne 1,3‐dipolar cycloaddition (CuAAC) is reported for the first time.
Bennion MC +13 more
europepmc +4 more sources
Atroposelective interrupted CuAAC reaction using cyclic diaryliodoniums [PDF]
Nature CommunicationsCopper-catalyzed azide–alkyne cycloaddition (CuAAC) is a pivotal strategy for joining two fragments, including bioactive moieties under mild conditions.
Yuanyuan Li +3 more
doaj +2 more sources
Site-specific bioconjugation of a murine dihydrofolate reductase enzyme by copper(I)-catalyzed azide-alkyne cycloaddition with retained activity. [PDF]
PLoS ONE, 2014 Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) is an efficient reaction linking an azido and an alkynyl group in the presence of copper catalyst. Incorporation of a non-natural amino acid (NAA) containing either an azido or an alkynyl group into a ...
Sung In Lim +4 more
doaj +6 more sources
Pathway selection between click and acyl transfer reactions driven by aminoacyl phosphates [PDF]
Nature CommunicationsCovalent transformations in biology follow defined temporal sequences that regulate processes such as acylation and phosphorylation, yet achieving comparable temporal control in synthetic systems remains challenging.
Debjyoti Bhattacharjee +6 more
doaj +2 more sources
inCu-click: DNA-enhanced ligand enables live-cell, intracellular click chemistry reaction with copper catalyst [PDF]
Nature CommunicationsLabeling cellular biomolecules via copper-catalyzed azide–alkyne cycloaddition (CuAAC) offers rapid reaction kinetics and uses small azide and alkyne probes that minimally disturb molecular function, making it ideal for tracking biomolecules.
Keqing Nian +6 more
doaj +2 more sources
Catalysis Communications, 2023 The demand for environmental friendly methodologies had shifted the the approach of scientific community for using easy and green reaction conditions instead of using hazardous and harsh reaction conditions.
Vijay Kumar +3 more
doaj +1 more source
Synthesis and CuAAC Reactions of Azidoalkylethoxysilanes: Grafting CuAAC Products onto Silica Surface [PDF]
Synthetic Communications, 2013 One-pot synthetic protocols of novel azido functionalized silane coupling agents from corresponding terminal mesylated or tosylated 1-olefins were developed. Azido groups were successfully converted to the corresponding 1,2,3-triazol ring by the copper-catalyzed azido alkyne coupling (CuAAC) reaction without alkoxysilane decomposition.
Kultyshev, Roman G. +3 more
openaire +1 more source
Beilstein Journal of Organic Chemistry, 2021 The development of long-wavelength photoinduced copper-catalyzed azide–alkyne click (CuAAC) reaction routes is attractive for organic and polymer chemistry.
Azra Kocaarslan +3 more
doaj +1 more source
CuAAC reactions of sterically hindered azides
Visnyk of the Lviv University. Series Chemistry, 2020 The regularities of the CuAAC reactions due to the structure of the substituent were determined and basic requirements for the choice of the catalytic system in the case of azides or alkynes with bulky substituents, and azides containing fragments able to effectively act on Cu(I) ions were shown.
R. Savka +4 more
openaire +2 more sources
A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling
Frontiers in Chemistry, 2021 Bioorthogonal chemistry allows rapid and highly selective reactivity in biological environments. The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is a classic bioorthogonal reaction routinely used to modify azides or alkynes that have been ...
Birthe Meineke +9 more
doaj +1 more source