Results 21 to 30 of about 12,742 (207)

Surface Modification of Melt Extruded Poly(ε-caprolactone) Nanofibers: Toward a New Scalable Biomaterial Scaffold. [PDF]

open access: yes, 2014
A photochemical modification of melt-extruded polymeric nanofibers is described. A bioorthogonal functional group is used to decorate fibers made exclusively from commodity polymers, covalently attach fluorophores and peptides, and direct cell growth ...
Baer, Eric   +5 more
core   +2 more sources

Folding of a donor–acceptor polyrotaxane by using noncovalent bonding interactions [PDF]

open access: yes, 2008
Mechanically interlocked compounds, such as bistable catenanes and bistable rotaxanes, have been used to bring about actuation in nanoelectromechanical systems (NEMS) and molecular electronic devices (MEDs).
A. Z. Stieg   +26 more
core   +3 more sources

Azides and Porphyrinoids: Synthetic Approaches and Applications. Part 2—Azides, Phthalocyanines, Subphthalocyanines and Porphyrazines

open access: yesMolecules, 2020
The reaction between organic azides and alkyne derivatives via the Cu(I)-catalyzed azide–alkyne cycloaddition (CuAAC) is an efficient strategy to combine phthalocyanines and analogues with different materials.
Ana R. L. Araújo   +8 more
doaj   +1 more source

Synthesis, Characterization and Chemistry of Tetrakis(Propargylisocyanide) Copper(I) Complex

open access: yesMolbank, 2023
The kinetically unstable propargylisocyanide was reacted with the tetrakis(acetonitrile) copper(I) hexafluorophosphate and the formed complex was then involved in a copper-catalyzed alkyne-azide cycloaddition reaction (CuAAC). After the decomplexation of
Alexandre Quelhas   +3 more
doaj   +1 more source

Phase transfer agent assisted biphasic CuAAC reaction

open access: yesRSC Advances, 2014
A phase transfer agent assisted biphasic Cu(I) catalyzed azide–alkyne 1,3-dipolar cycloaddition (CuAAC) reaction system was developed. A biphasic reaction medium consisting of water and an organic solvent ensures the dissolution of reagents and substrates. Tris(triazolylmethyl)amine ligands with an appropriate hydrophilic–lipophilic balance are able to
Jae Hyun Kim, Sanghee Kim
openaire   +1 more source

Designer Reagents for Mass Spectrometry-Based Proteomics: Clickable Cross-Linkers for Elucidation of Protein Structures and Interactions [PDF]

open access: yes, 2012
We present novel homobifunctional amine-reactive clickable cross-linkers (CXLs) for investigation of three-dimensional protein structures and protein–protein interactions (PPIs).
Agnew, Heather D.   +11 more
core   +2 more sources

A flow platform for degradation-free CuAAC bioconjugation

open access: yesNature Communications, 2018
Cu-catalyzed azide-alkyne cycloaddition (CuAAC) reaction is a common bioconjugation technique; however oxidative degradation and residual copper may limit its use.
Marine Z. C. Hatit   +5 more
doaj   +1 more source

A detailed study on understanding glycopolymer library and Con A interactions [PDF]

open access: yes, 2013
Synthetic glycopolymers are important natural oligosaccharides mimics for many biological applications. To develop glycopolymeric drugs and therapeutic agents, factors that control the receptor-ligand interaction need to be investigated.
Becer, C. Remzi   +5 more
core   +1 more source

Recent syntheses of steroid derivatives using the CuAAC “click” reaction

open access: yesArkivoc, 2021
The introduction of heterocycles into steroids is often at the origin of a modification of their physiological activity and thus allows the formation of new biologically interesting molecules. Recent advances in the field of steroid synthesis using the copper-catalyzed azide-alkyne cycloaddition (CuAAC) are presented here.
Ibrahim-Ouali, Malika, Dumur, Frédéric
openaire   +3 more sources

Copper-Catalyzed Azide–Alkyne Cycloaddition-Oriented Multifunctional Bio-Orthogonal Linker BPPA: Design, Synthesis and Evaluation

open access: yesMolecules, 2023
The multifunctional linker molecules are crucial for the bio-orthogonal reaction for proteomic target profiling. Herein, we wish to present a novel type of biotin-based tetra-functional bio-orthogonal linkers 3a–3h named BPPA which, possessing a unique ...
Shuo Wang, Xu He, Junchen Li, Enxue Shi
doaj   +1 more source

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