Results 81 to 90 of about 15,690 (247)

Copper(I)-catalyzed tandem reaction: synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and alkynes

Beilstein Journal of Organic Chemistry, 2018
A copper-catalyzed azide–alkyne cycloaddition (CuAAC) reaction for the synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and terminal alkynes is reported.
Muhammad Israr, Changqing Ye, Munira Taj Muhammad, Yajun Li, Hongli Bao   +4 more
doaj   +1 more source

Solvent-Free Copper-Catalyzed Azide-Alkyne Cycloaddition under Mechanochemical Activation

Molecules, 2015
The ball-mill-based mechanochemical activation of metallic copper powder facilitates solvent-free alkyne-azide click reactions (CuAAC). All parameters that affect reaction rate (i.e., milling time, revolutions/min, size and milling ball number) have been
Laura Rinaldi, Katia Martina, Francesca Baricco, Laura Rotolo, Giancarlo Cravotto   +4 more
doaj   +1 more source

Synthesis of Phospholipid-Protein Conjugates as New Antigens for Autoimmune Antibodies

Molecules, 2015
Copper(I)-catalyzed azide-alkyne cycloaddition, or CuAAC click chemistry, is an efficient method for bioconjugation aiming at chemical and biological applications.
Arindam Maity, Claudia Macaubas, Elizabeth Mellins, Kira Astakhova   +3 more
doaj   +1 more source

inCu-click: DNA-enhanced ligand enables live-cell, intracellular click chemistry reaction with copper catalyst

Nature Communications
Labeling cellular biomolecules via copper-catalyzed azide–alkyne cycloaddition (CuAAC) offers rapid reaction kinetics and uses small azide and alkyne probes that minimally disturb molecular function, making it ideal for tracking biomolecules.
Keqing Nian, Yifang Liu, Yuchen Qiu, Zhuoyu Zhang, Laura Brigandi, Meni Wanunu, Sara H. Rouhanifard   +6 more
doaj   +1 more source

Stepwise, Protecting Group Free Synthesis of [4]Rotaxanes

Molecules, 2017
Despite significant advances in the last three decades towards high yielding syntheses of rotaxanes, the preparation of systems constructed from more than two components remains a challenge.
James E. M. Lewis, Joby Winn, Stephen M. Goldup   +2 more
doaj   +1 more source

Fluorophore-Assisted Click Chemistry through Copper(I) Complexation

Biomolecules, 2020
The copper-catalyzed alkyne-azide cycloaddition (CuAAC) is one of the most powerful chemical strategies for selective fluorescent labeling of biomolecules in in vitro or biological systems. In order to accelerate the ligation process and ensure efficient
Victor Flon, Magalie Bénard, Damien Schapman, Ludovic Galas, Pierre-Yves Renard, Cyrille Sabot   +5 more
doaj   +1 more source

Mechanism of CuAAC reaction: In acetic acid and aprotic conditions

Journal of Molecular Catalysis A: Chemical, 2017
Abstract Protonation of copper-triazolide is a distinctive and final part in CuAAC reaction which has kinetic importance such that it can even affect the product distribution. In the context of this study, the protonation mechanism of copper-triazolide was investigated with quantum mechanical calculations to have a deeper understanding of the ...
Ozen, Cihan, Tuzun, Nurcan Senyurt
openaire   +2 more sources

Dinuclear thiazolylidene copper complex as highly active catalyst for azid–alkyne cycloadditions

Beilstein Journal of Organic Chemistry, 2016
A dinuclear N-heterocyclic carbene (NHC) copper complex efficiently catalyzes azide–alkyne cycloaddition (CuAAC) “click” reactions. The ancillary ligand comprises two 4,5-dimethyl-1,3-thiazol-2-ylidene units and an ethylene linker.
Anne L. Schöffler, Ata Makarem, Frank Rominger, Bernd F. Straub   +3 more
doaj   +1 more source

Revisiting the mechanism of the mono nuclear copper-catalyzed cycloaddition of azide and alkynes (CuAAC) by the topology of .... [PDF]

, 2013
Comunicación presentada y aceptada en el CHITEL2013, XXXIX International Conference THEORETICAL CHEMISTS OF LATIN EXPRESSION (XXXIX Congreso Internacional de Químicos de Expresión Latina).Se analiza el mecanismo de la reacción de cicloadición, catalizada
Calvo-Losada, Saturnino, Pino-Gonzalez, Maria Soledad, Quirante-Sanchez, Jose Joaquin   +2 more
core  

Synthesis of fluorinated polypropylene using CuAAC click chemistry

Journal of Applied Polymer Science, 2018
ABSTRACTSynthesis of fluorine containing polypropylene (PPF) from chlorinated polypropylene (PPCl) via Cu(I) catalyzed Huisgen type 1,3‐dipolar cycloaddition (CuAAC) and its water repellency properties are demonstrated. Initially, clickable azido‐functional polypropylene (PPN3) and alkyne‐functionalized fluorine compound (FAl) are independently ...
G. Acik, C. Elif Cansoy, M. A. Tasdelen
openaire   +2 more sources