Results 61 to 70 of about 6,459 (197)

Stepwise, Protecting Group Free Synthesis of [4]Rotaxanes

Molecules, 2017
Despite significant advances in the last three decades towards high yielding syntheses of rotaxanes, the preparation of systems constructed from more than two components remains a challenge.
James E. M. Lewis, Joby Winn, Stephen M. Goldup   +2 more
doaj   +1 more source

Mechanism of CuAAC reaction: In acetic acid and aprotic conditions

Journal of Molecular Catalysis A: Chemical, 2017
Abstract Protonation of copper-triazolide is a distinctive and final part in CuAAC reaction which has kinetic importance such that it can even affect the product distribution. In the context of this study, the protonation mechanism of copper-triazolide was investigated with quantum mechanical calculations to have a deeper understanding of the ...
Ozen, Cihan, Tuzun, Nurcan Senyurt
openaire   +2 more sources

Fluorophore-Assisted Click Chemistry through Copper(I) Complexation

Biomolecules, 2020
The copper-catalyzed alkyne-azide cycloaddition (CuAAC) is one of the most powerful chemical strategies for selective fluorescent labeling of biomolecules in in vitro or biological systems. In order to accelerate the ligation process and ensure efficient
Victor Flon, Magalie Bénard, Damien Schapman, Ludovic Galas, Pierre-Yves Renard, Cyrille Sabot   +5 more
doaj   +1 more source

Synthesis of fluorinated polypropylene using CuAAC click chemistry

Journal of Applied Polymer Science, 2018
ABSTRACTSynthesis of fluorine containing polypropylene (PPF) from chlorinated polypropylene (PPCl) via Cu(I) catalyzed Huisgen type 1,3‐dipolar cycloaddition (CuAAC) and its water repellency properties are demonstrated. Initially, clickable azido‐functional polypropylene (PPN3) and alkyne‐functionalized fluorine compound (FAl) are independently ...
G. Acik, C. Elif Cansoy, M. A. Tasdelen
openaire   +2 more sources

Dinuclear thiazolylidene copper complex as highly active catalyst for azid–alkyne cycloadditions

Beilstein Journal of Organic Chemistry, 2016
A dinuclear N-heterocyclic carbene (NHC) copper complex efficiently catalyzes azide–alkyne cycloaddition (CuAAC) “click” reactions. The ancillary ligand comprises two 4,5-dimethyl-1,3-thiazol-2-ylidene units and an ethylene linker.
Anne L. Schöffler, Ata Makarem, Frank Rominger, Bernd F. Straub   +3 more
doaj   +1 more source

Polymeric Micellar Nanocatalysts for CuAAC Click Reaction in Water

Langmuir
Polymer-supported copper catalysts have attained a prominent status and continue to be a focal point of ongoing research and development due to their adaptable properties, which make them invaluable tools for diverse catalytic reactions in aqueous solutions.
Witsanu Sombat, Panuwat Padungros, Voravee P. Hoven   +2 more
openaire   +2 more sources

Heterogeneous catalysis for azide-alkyne bioconjugation in solution via spin column: Attachment of dyes and saccharides to peptides and DNA

BioTechniques, 2015
Copper-catalyzed azide-alkyne cycloaddition (CuAAC) “click” chemistry is widely used and has demonstrated particular utility for bio-orthogonal conjugation reactions.
Jeremy Kallick, Sarah Harris, Andrew K. Udit, Michael G. Hill   +3 more
doaj   +1 more source

Polypropylene-based graft copolymers via CuAAC click chemistry

eXPRESS Polymer Letters, 2018
Graft copolymers from commercial chlorinated polypropylene (PP-Cl) possessing either poly(ethylene glycol) (PEG) or poly(ε-caprolactone) (PCL) grafts are synthesized by copper (I)-catalyzed azide-alkyne cycloaddition ‘click’ reaction (CuAAC).
G. Acik, E. Sey, M. A. Tasdelen
doaj   +1 more source

One-Pot Synthesis of Imidazo[1,2-a]pyridines via Groebke–Blackburn–Bienaymé Reaction and CuAAC Assisted by MW

Chemistry Proceedings
Bis-heterocyclic compounds containing imidazo[1,2-a]pyridines (IMPs) are privileged heterocyclic drug scaffolds due to their potential applications. The Groebke–Blackburn–Bienaymé reaction (GBBR) is a greener alternative to synthesizing IMPs.
Manuel A. Rentería-Gómez, David Calderón-Rangel, Fidel Rodríguez-López, Alejandro Corona-Díaz, Rocío Gámez-Montaño   +4 more
doaj   +1 more source

Efficient One-Pot Synthesis of Triazole-Linked Morpholinone Scaffolds by CuAAC in the Presence of 18-Crown-6

SynOpen, 2018
A range of bis-heterocyclic derivatives based on novel morpholinone­ and triazole heterocycles was prepared from iodo-morpholinone­. The key step in our strategy is a one-pot procedure based upon copper-catalysed alkyne-azide cycloaddition (CuAAC) from ...
A. Mayooufi, M. Romdhani-Younes, J. Thibonnet   +2 more
doaj   +1 more source