Results 51 to 60 of about 15,378 (241)

Triazole-Directed Pd-Catalyzed C(sp2)–H Oxygenation of Arenes and Alkenes [PDF]

, 2016
Selective Pd-catalyzed C(sp2)–H oxygenation of 4-substituted 1,2,3-triazoles is described. Unlike previous metal-catalyzed C–H functionalization events, which preferentially occur at the activated heterocyclic C–H bond, the regioselective oxygenation of ...
Aizpurua Iparraguirre, Jesús María, Correa Navarro, Arkaitz, Irastorza Epelde, Aitziber   +2 more
core   +2 more sources

Coordinatively unsaturated ruthenium complexes as efficient alkyne-azide cycloaddition catalysts [PDF]

, 2012
The performance of 16-electron ruthenium complexes with the general formula Cp*Ru(L)X (in which L = phosphine or N-heterocyclic carbene ligand; X = Cl or OCH2CF3) was explored in azide−alkyne cycloaddition reactions that afford the 1,2,3- triazole ...
Broggi, Julie, Cavallo, Luigi, Fortman, George C., Lamberti, Marina, Nolan, Steven P., Poater, Albert, Slawin, Alexandra M. Z.   +6 more
core   +2 more sources

Intrabandgap States Engineering in Functionalized Nanodiamond to Generate Solvated Electrons for Photocatalysis Under Solar Illumination

Advanced Functional Materials, EarlyView.
The negative electron affinity of diamond allows to emit highly reductive electrons. By introducing intra‐bandgap states and an optimized electron transfer mechanism by surface functionalization with Ru(bpy)3, the formation of solvated electrons is achieved upon solar irradiation.
Benjamin Kiendl, Arsène Chemin, Adam H. Day, Rocio B. Rodriguez, Sneha Choudhury, Franziska Buchner, Kaan Atak, Christoph Merschjann, Emina Hadzifejzovic, Tim D. W. Claridge, Karin Larsson, Amélie Venerosy, Mailis M. Lounasvuori, Natalia Zabarska, Boyan Iliev, Thomas J. S. Schubert, Hugues A. Girard, Jean‐Charles Arnault, John S. Foord, Tristan Petit, Anke Krueger   +20 more
wiley   +1 more source

Anomeric O-Functionalization of Carbohydrates for Chemical Conjugation to Vaccine Constructs. [PDF]

, 2018
Carbohydrates mediate a wide range of biological interactions, and understanding these processes benefits the development of new therapeutics. Isolating sufficient quantities of glycoconjugates from biological samples remains a significant challenge ...
Gervay-Hague, Jacquelyn, Hsieh, Hsiao-Wu, Park, Simon S   +2 more
core   +1 more source

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

Advanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella, Kobra Azizi, Dirk M. Guldi, Tomás Torres   +3 more
wiley   +1 more source

Design, Modeling and Synthesis of 1,2,3-Triazole-Linked Nucleoside-Amino Acid Conjugates as Potential Antibacterial Agents

Molecules, 2017
Copper-catalyzed azide-alkyne cycloadditions (CuAAC or click chemistry) are convenient methods to easily couple various pharmacophores or bioactive molecules.
Sarah N. Malkowski, Carolyn F. Dishuck, Gene G. Lamanilao, Carter P. Embry, Christopher S. Grubb, Mauricio Cafiero, Larryn W. Peterson   +6 more
doaj   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Development of Novel Immobilized Copper–Ligand Complex for Click Chemistry of Biomolecules

Molecules
Copper-catalyzed azide–alkyne cycloaddition click (CuAAC) reaction is widely used to synthesize drug candidates and other biomolecule classes. Homogeneous catalysts, which consist of copper coordinated to a ligand framework, have been optimized for high ...
Rene Kandler, Yomal Benaragama, Manoranjan Bera, Caroline Wang, Rasheda Aktar Samiha, W. M. C. Sameera, Samir Das, Arundhati Nag   +7 more
doaj   +1 more source

Noncanonical Amino Acids in the Interrogation of Cellular Protein Synthesis [PDF]

, 2011
Proteins in living cells can be made receptive to bioorthogonal chemistries through metabolic labeling with appropriately designed noncanonical amino acids (ncAAs).
Ngo, John T., Tirrell, David A.
core   +2 more sources

Synthesis of fluorinated polypropylene using CuAAC click chemistry

Journal of Applied Polymer Science, 2018
ABSTRACTSynthesis of fluorine containing polypropylene (PPF) from chlorinated polypropylene (PPCl) via Cu(I) catalyzed Huisgen type 1,3‐dipolar cycloaddition (CuAAC) and its water repellency properties are demonstrated. Initially, clickable azido‐functional polypropylene (PPN3) and alkyne‐functionalized fluorine compound (FAl) are independently ...
G. Acik, C. Elif Cansoy, M. A. Tasdelen
openaire   +2 more sources