Results 31 to 40 of about 11,111 (220)
, 2022 Copper(I)-catalyzed alkyne–azide cycloaddition (CuAAC) is a resourceful and stereospecific methodology that has considerably yielded promising 1,2,3-triazole-appended “click” scaffolds with the potential for selective metal ion recognition.
Harminder Singh (743205) +7 more
core +1 more source
Beilstein Journal of Organic Chemistry, 2021 The development of long-wavelength photoinduced copper-catalyzed azide–alkyne click (CuAAC) reaction routes is attractive for organic and polymer chemistry.
Azra Kocaarslan +3 more
doaj +1 more source
Recent syntheses of steroid derivatives using the CuAAC “click” reaction
, 2021 International audienceThe introduction of heterocycles into steroids is often at the origin of a modification of their physiological activity and thus allows the formation of new biologically interesting molecules. Recent advances in the field of steroid
Dumur, Frédéric, Ibrahim-Ouali, Malika
core +1 more source
Multicyclic peptides manufactured via scaffold-assisted CLIPS/CuAAC technology [PDF]
, 2018 Cyclic peptides have emerged as a highly potent class of molecules for therapeutic applications. So far, reported synthetic methodologies for the production of cyclic peptides mostly focus on mono- and bicyclic constructs, as the synthesis of higher ...
Richelle, G.J.J.
core +6 more sources
Copper on Calcium Carbonate and Marble Waste as Recyclable Catalysts for Ultrasound-Assisted One-Pot Synthesis of 1,4-Disubstituted 1,2,3-Triazoles. [PDF]
ChemSusChemA sustainable CaCO3‐supported copper catalyst, prepared by simple adsorption of Cu(II) onto natural and marble waste‐derived carbonate materials, promotes ultrasound‐assisted CuAAC reaction in water. The work provides straightforward access to 1,4‐disubstituted 1,2,3‐triazoles under mild conditions while combining catalyst recyclability with the ...
Serra R +8 more
europepmc +2 more sources
Metabolic Labeling and Visualization of Isoprenoids Using Alkyne-Modified DMAPP Analogs in Bacillus subtilis. [PDF]
Angew Chem Int Ed EnglFluorescence‐based visualization and targeted mass–spectrometric enrichment of membrane‐embedded isoprenoids in Bacillus subtilis via cell‐permeant, alkynylated DMAPP analogs. ABSTRACT Isoprenoids are a chemically and functionally diverse class of metabolites that underlie essential bacterial physiology including respiration and cell envelope ...
Hulsey ZN +7 more
europepmc +3 more sources
Carbohydrate CuAAC click chemistry for therapy and diagnosis
Carbohydrate Research, 2016 Carbohydrates are important as signaling molecules and for cellular recognition events, therefore offering scope for the development of carbohydrate-mimetic diagnostics and drug candidates. As a consequence, the construction of carbohydrate-based bioactive compounds and sensors has become an active research area. While the advent of click chemistry has
He, Xiao Peng +5 more
openaire +3 more sources
CuAAC reactions of sterically hindered azides
Visnyk of the Lviv University. Series Chemistry, 2020 The regularities of the CuAAC reactions due to the structure of the substituent were determined and basic requirements for the choice of the catalytic system in the case of azides or alkynes with bulky substituents, and azides containing fragments able to effectively act on Cu(I) ions were shown.
R. Savka +4 more
openaire +2 more sources
Structural Determinants of Alkyne Reactivity in Copper-Catalyzed Azide-Alkyne Cycloadditions
Molecules, 2016 This work represents our initial effort in identifying azide/alkyne pairs for optimal reactivity in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
Xiaoguang Zhang, Peiye Liu, Lei Zhu
doaj +1 more source
Molecules, 2020 The reaction between organic azides and alkyne derivatives via the Cu(I)-catalyzed azide–alkyne cycloaddition (CuAAC) is an efficient strategy to combine phthalocyanines and analogues with different materials.
Ana R. L. Araújo +8 more
doaj +1 more source