Tunable, Functional Diblock Copolypeptide Hydrogels Based on Methionine Homologs. [PDF]
The preparation of new diblock copolypeptide hydrogels derived from homologs of l-methionine, that is, l-homomethionine and l-6-(methylthio)-l-norleucine is described.
Deming, Timothy J +2 more
core +1 more source
Polymeric Micellar Nanocatalysts for CuAAC Click Reaction in Water
Polymer-supported copper catalysts have attained a prominent status and continue to be a focal point of ongoing research and development due to their adaptable properties, which make them invaluable tools for diverse catalytic reactions in aqueous solutions.
Witsanu Sombat +2 more
openaire +2 more sources
A ribose-functionalized NAD+ with unexpected high activity and selectivity for protein poly-ADP-ribosylation. [PDF]
Nicotinamide adenine dinucleotide (NAD+)-dependent ADP-ribosylation plays important roles in physiology and pathophysiology. It has been challenging to study this key type of enzymatic post-translational modification in particular for protein poly-ADP ...
Chen, Jingwen +9 more
core +1 more source
Noncanonical Amino Acids in the Interrogation of Cellular Protein Synthesis [PDF]
Proteins in living cells can be made receptive to bioorthogonal chemistries through metabolic labeling with appropriately designed noncanonical amino acids (ncAAs).
Ngo, John T., Tirrell, David A.
core +2 more sources
A One Pot Synthesis of Diketopiperazines via Multicomponent Reactions Based on Isocyanides
2,5-DKPs are heterocyclic peptidomimetics, present in nature with high structural diversity, popular in the design of new bioactive molecules with potential application in medicinal chemistry, exhibiting anticancer and antimicrobial properties, among ...
Alejandro Corona-Díaz +4 more
doaj +1 more source
Selective C(sp2)−H Halogenation of "click" 4-Aryl-1,2,3-triazoles [PDF]
Selective bromination reactions of “click compounds” are described. Electron-neutral and electron-deficient arenes selectively undergo unprecedented Pd-catalyzed C–H ortho-halogenations assisted by simple triazoles as modular directing groups, whereas ...
Correa Navarro, Arkaitz +2 more
core +3 more sources
Stepwise, Protecting Group Free Synthesis of [4]Rotaxanes
Despite significant advances in the last three decades towards high yielding syntheses of rotaxanes, the preparation of systems constructed from more than two components remains a challenge.
James E. M. Lewis +2 more
doaj +1 more source
Reactive precursor particles as synthetic platform for the generation of functional nanoparticles, nanogels, and microgels [PDF]
Precise control of the chemical functionality of polymer nanoparticles is a key requirement in tailoring their (dynamic) colloidal properties toward advanced applications.
Gruber, Alexandra +2 more
core +1 more source
Three-component one-pot synthesis of benzothiazolopyrimidine derivatives through a CuAAC/ring cleavage/cyclization process.
Weiguang Yang +5 more
openaire +2 more sources
Fluorinated maleimide-substituted porphyrins and chlorins: synthesis and characterization
Maleimide-containing fluorinated porphyrins and chlorins were prepared based on the reaction of Zn(II) or Ni(II) complexes of 5,10,15,20-tetrakis(4-amino-2,3,5,6-tetrafluorophenyl)porphyrin and chlorin with maleic anhydride.
Valentina A. Ol’shevskaya +2 more
doaj +1 more source

