Results 161 to 170 of about 2,327 (197)

Cucurbitacins: Nature’s Wonder Molecules

Current Traditional Medicine, 2022
Abstract: Over the past decades, several natural constituents belonging to different classes have been isolated from plants for medicinal purposes. Cucurbitacins is one such type of natural compound. Cucurbitacin is a class of biochemical compounds that some plants, notably members of the pumpkin and gourd family, Cucurbitaceae produce and function as
Sonal H. Kanani, Devang J. Pandya
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Cucurbitacins from Bacopa monnieri☆

Phytochemistry, 2007
Four cucurbitacins, bacobitacin A-D (1-4) as well as, a known cytotoxic, cucurbitacin E (5) together with three known phenylethanoid glycosides, monnieraside I, III and plantioside B were isolated form the aerial part of Bacopa monnieri. Their structures were elucidated on the basis of extensive spectroscopic investigations (1D, 2D NMR and ESI-QTOF-MS ...
Pamita, Bhandari, Neeraj, Kumar, Bikram, Singh, Vijay K, Kaul   +3 more
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Antiangiogenic effects of cucurbitacin-I

Archives of Pharmacal Research, 2014
Cucurbitacin-I is a naturally occurring tetracyclic triterpenoid compound with diverse physiological actions that include inducing apoptosis and blocking cell cycle progression of various cancer cells. However, its antiangiogenic activity has not yet been examined.
Hyeon Jin, Kim, Jin-Kyung, Kim
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Cucurbitacin glycosides from Caput nigri

Phytochemistry, 1995
The chemical structures of cabenosides I-L were investigated. These are four of the 12 cucurbitacin glycosides isolated from 'Cabeça-de-negro', the roots of Caput nigri. By means of chemical analyses the structures of cabenosides I-L were elucidated as 10 alpha-cucurbit-5-ene-3 beta,11 alpha,20S,24 xi,25-pentaol [3, 25-di-O-beta-D-glucopyranoside, and ...
K, Nakano, Y, Kanai, K, Murakami, Y, Takaishi   +3 more
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Cucurbitacins

Journal of Chemical Ecology, 1985
Four species of diabroticites with different host specificities are shown for the first time to sequester cucurbitacins. While all beetles fed on an artificial diet (no cucurbitacins) were readily consumed by Chinese praying mantids, a significant proportion of adultDiabrotica balteata (72%),D. undecimpunctata howardi (46%), andD.
J E, Ferguson, R L, Metcalf
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Cucurbitacins From Bryonia Verrucosa. Isomerization of 2-Hydroxy-3-Keto-Cucurbitacins

Natural Product Letters, 1999
Abstract Three new cucurbitacins as well as thirteen known ones were isolated from the fruits of Bryonia verrucosa. the new compounds were characterized by chemical and spectral methods. an effective and simple method to isomerize 2-hydroxy-3-keto-cucurbitacins in acid media is described.
Antonio Galindo, Nelson Villegas, Horacio Mansilla   +2 more
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A new cucurbitacin profile forCucurbita andreana: A candidate for cucurbitacin tissue culture

Journal of Chemical Ecology, 1993
In addition to previously reported cucurbitacins B,1, and D,2, cucurbitacin E,3, and I,4, aglycones and their glucosides 2-O-β-glucopyranosyl-cucurbitacin E,5, and 2-O-β-glucopyranosyl-cucurbitacin I,6, were isolated and identified as constituents ofCucurbita andreana on the basis of MS, FD-MS, 1 H NMR and(13)C NMR spectroscopy.
F T, Halaweish, D W, Tallamy
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Cucurbitacins of Colocynthis vulgaris

Phytochemistry, 1988
Abstract The methanolic extract of the fruits of Colocynthis vulgaris on acidic hydrolysis afforded in addition to cucurbitacin I and J a new cucurbitacin designated cucurbitacin T whose structure was elucidated as (24 S )-16,24-anhydro-25-methoxy-2,16α,20β,24-tetrahydroxy-3,11,22-trioxocucurbita-1,5-diene by spectroscopic methods. The biosynthetic
Chandra B. Gamlath, A.A.Leslie Gunatilaka, Khisal A. Alvi, null Atta-ur-Rahman, Sinnathamby Balasubramaniam   +4 more
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Cucurbitacin B and cucurbitacin I suppress adipocyte differentiation through inhibition of STAT3 signaling

Food and Chemical Toxicology, 2014
Cucurbitacin B, a member of the cucurbitaceae family, can act as a STAT3 signaling inhibitor to regulate the growth of hepatocellular carcinoma. STAT3 signaling has been shown to inhibit adipocyte differentiation through C/EBPα and PPARγ. Based on these studies, we hypothesized that cucurbitacin B would prevent PPARγ mediated adipocyte differentiation ...
Cho-Rong, Seo, Dong Kwon, Yang, No-Joon, Song, Ui Jeong, Yun, A-Ryeong, Gwon, Dong-Gyu, Jo, Jae Youl, Cho, Keejung, Yoon, Jee-Yin, Ahn, Chu Won, Nho, Woo Jin, Park, Seung Yul, Yang, Kye Won, Park   +12 more
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Cucurbitacin Contents in Hemsleya dolichocarpa

The American Journal of Chinese Medicine, 1991
Hemsleya dolichocarpa was studied for its cucurbitacin contents during growing period. A colorimetric method was used to determine the total cucurbitacin levels, and a TLC densitometric assay was employed for estimating dihydrocucurbitacin F and its acetate, two active principles in Hemsleya plants. Cucurbitacin contents rise progressively from May to
P Q, Yang, S Y, Liu, Z H, Cao, W J, Chang, C T, Che   +4 more
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