Results 61 to 70 of about 1,810,948 (240)

Development and validation of an open-source virtual reality environment for alcohol use disorder and determinants of cue-induced craving among Indian participants

Indian Journal of Psychiatry
Background: Alcohol use disorder (AUD) is a chronic relapsing illness that causes significant morbidity. Craving is a key factor responsible for relapse in AUD. Cue exposure (CE) has attempted as an assessment and therapeutic procedure in AUD.
Tamonud Modak, Sanjukta Ghosh, Abhijit R. Rozatkar   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Changes in the Relative Balance of Approach and Avoidance Inclinations to Use Alcohol Following Cue Exposure Vary in Low and High Risk Drinkers

Frontiers in Psychology, 2017
According to the ambivalence model of craving, alcohol craving involves the dynamic interplay of separate approach and avoidance inclinations. Cue-elicited increases in approach inclinations are posited to be more likely to result in alcohol consumption ...
Ross C. Hollett, Werner G. K. Stritzke, Phoebe Edgeworth, Michael Weinborn   +3 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

How does food-cue exposure lead to overeating?

, 2008
Exposure to the sight and smell of food increases subsequent food intake. This study explored the reason why over-consumption occurs. Three hypotheses were considered: cue exposure (1) increases the amount of food that people want to eat, (2) increases ...
Ferriday, D, Brunstrom, JM
core   +1 more source

Adolescent male and female rats show enhanced latent inhibition of conditioned fear compared to adult rats

Frontiers in Behavioral Neuroscience
IntroductionLatent inhibition is diminished associative memory because of pre-exposure to the conditioned stimulus without any consequences. Latent inhibition likely plays a significant role in the ontogeny of anxiety disorders, contributing to why ...
Christina J. Perry, Christina J. Perry, Ricky John, Han B. Trinh, Brandon K. Richards, Katherine D. Drummond, Chun Hui J. Park, Chun Hui J. Park, Chun Hui J. Park, Jee Hyun Kim, Jee Hyun Kim, Jee Hyun Kim   +11 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Effects of Repeated Cue Exposure on Cannabis Craving [PDF]

, 2015
Craving is a key element of the cannabis withdrawal syndrome that has been associated with continued use and relapse. Although cue-induced cannabis craving has been established in single laboratory sessions, procedures to sustain craving over multiple ...
Fogel, Jessica S
core   +1 more source