Results 71 to 80 of about 1,899,596 (290)

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Development and validation of an open-source virtual reality environment for alcohol use disorder and determinants of cue-induced craving among Indian participants

Indian Journal of Psychiatry
Background: Alcohol use disorder (AUD) is a chronic relapsing illness that causes significant morbidity. Craving is a key factor responsible for relapse in AUD. Cue exposure (CE) has attempted as an assessment and therapeutic procedure in AUD.
Tamonud Modak, Sanjukta Ghosh, Abhijit R. Rozatkar   +2 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Counterconditioning reduces cue-induced craving and actual cue-elicited consumption [PDF]

, 2010
Cue-induced craving is not easily reduced by an extinction or exposure procedure and may constitute an important route toward relapse in addictive behavior after treatment. In the present study, we investigated the effectiveness of counterconditioning as
Baeyens, Frank, van Gucht, D., Hermans, Dirk, Beckers, T., Frank Baeyens, Tom Beckers, Debora Vansteenwegen, Dirk Hermans, Hermans, D., Vansteenwegen, Debora, Vansteenwegen, D., Dinska Van Gucht, Baeyens, F., Beckers, Tom, Van Gucht, Dinska   +14 more
core   +1 more source

Nicotine Craving and Cue-Exposure Therapy [PDF]

Logos Universality Mentality Education Novelty. Section: SOCIAL SCIENCES, 2015
Smoking is affecting global population, causing different cardiovascular disease, respiratory disease, cancer, asthma and kidney problems. Although it can be prevented, smoking is one of the major causes of death all over the world. Smoking is a social activity that depending on the context may have different meanings for smokers even if they are aware
openaire   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Adolescent male and female rats show enhanced latent inhibition of conditioned fear compared to adult rats

Frontiers in Behavioral Neuroscience
IntroductionLatent inhibition is diminished associative memory because of pre-exposure to the conditioned stimulus without any consequences. Latent inhibition likely plays a significant role in the ontogeny of anxiety disorders, contributing to why ...
Christina J. Perry, Christina J. Perry, Ricky John, Han B. Trinh, Brandon K. Richards, Katherine D. Drummond, Chun Hui J. Park, Chun Hui J. Park, Chun Hui J. Park, Jee Hyun Kim, Jee Hyun Kim, Jee Hyun Kim   +11 more
doaj   +1 more source

Changes in the Relative Balance of Approach and Avoidance Inclinations to Use Alcohol Following Cue Exposure Vary in Low and High Risk Drinkers

Frontiers in Psychology, 2017
According to the ambivalence model of craving, alcohol craving involves the dynamic interplay of separate approach and avoidance inclinations. Cue-elicited increases in approach inclinations are posited to be more likely to result in alcohol consumption ...
Ross C. Hollett, Werner G. K. Stritzke, Phoebe Edgeworth, Michael Weinborn   +3 more
doaj   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source