Results 71 to 80 of about 1,810,948 (240)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Table_1_Neural Correlates of Food Cue Exposure Intervention for Obesity: A Case-Series Approach.docx

, 2020
BackgroundPeople with overweight have stronger reactivity (e.g., subjective craving) to food cues than lean people, and this reactivity is positively associated with food intake.
Karolien van den Akker (8740308), Anita Jansen (8740302), Anne Roefs (8740311), Ghislaine Schyns (8740305), Sieske Franssen (8740299)   +4 more
core   +1 more source

Eating behavior in restrained and unrestrained eaters after food-cue exposure: examining the cue reactivity and counteractive-control models [PDF]

, 2009
Many studies have demonstrated that those high in weight-related concerns cat more after food-cue exposure, which is consistent with predictions of the cue reactivity model.
Roefs, A.J.; id_orcid, Jansen, A.T.M.; id_orcid, Coelho, J., Jansen, A.T.M., Nederkoorn, C., Roefs, A.J.   +5 more
core   +2 more sources

Applying the health belief model to understand smoking craving among adults in Selangor, Malaysia

Discover Public Health
Background Cigarette craving is a central driver of nicotine dependence and relapse, yet limited research has examined craving using cognitive–behavioural health frameworks. This study investigated the predictors of smoking craving among Malaysian adults
Subramaniam Munusamy, Shaufique F. Sidique, Norashidah M. Nor, Ezamin A. Rahim   +3 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Self‐Regulated Learning Meets AI: Reinterpreting Self‐Regulation, Co‐Regulation, and Socially Shared Regulation in Human–AI Interaction

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Advancing artificial intelligence (AI) has transformed learning and work, yet higher education and professional development programs have not systematically equipped learners for AI‐prevalent environments. This lack of preparation creates uncertainty regarding control, responsibility, trust, and accountability.
Moon‐Heum Cho, Jerusalem Merkebu
wiley   +1 more source

Cue-Reminders to Prevent Health-Risk Behaviors: A Systematic Review

Frontiers in Public Health, 2019
Introduction: It has been proposed that the use of cue-reminders may increase the effectiveness of interventions that aim to prevent health-risk behaviors (i.e., having unsafe sex, unhealthy dietary intake, lack of physical activity, and substance use ...
Lonneke van Leeuwen, Simone Onrust, Bas van den Putte, Bas van den Putte, Marloes Kleinjan, Marloes Kleinjan, Lex Lemmers, Rutger C. M. E. Engels, Roel C. J. Hermans, Roel C. J. Hermans   +9 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

When trauma triggers craving: meta-analytic evidence for the mediating role of negative affect among trauma-exposed individuals who use substances

European Journal of Psychotraumatology
Background: In experimental studies using the cue reactivity paradigm (CRP), classically conditioned substance craving is well-documented among individuals who use substances with trauma histories.
Sarah DeGrace, Martin M. Smith, Mikaela A. Ethier-Gagnon, Tessa Cosman, Simon B. Sherry, Pablo Romero-Sanchiz, Brian Bird, Philip G. Tibbo, Igor Yakovenko, Sherry H. Stewart   +9 more
doaj   +1 more source