Results 71 to 80 of about 17,236 (327)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The efficacy of cue exposure with response prevention in extinguishing drug and alcohol cue reactivity [PDF]

, 2007
It has been suggested that drug cue-elicited urges and psychophysiological reactions are the results of Pavlovian conditioning processes and that it should be possible to extinguish these responses with cue exposure with response prevention.
Jansen, A.T.M.; id_orcid, Havermans, R.C.; id_orcid, Mulkens, S.; id_orcid, Mulkens, S., Nederkoorn, C., Jansen, A.T.M., Havermans, R.C.   +6 more
core   +1 more source

Striatal alcohol cue-reactivity is stronger in male than female problem drinkers [PDF]

, 2019
Despite apparent sex differences in the development and treatment of alcohol use disorder, relatively little is known about the underlying neural mechanisms.
Pattij, Tommy, Goudriaan, Anna E., Wiers, Reinout W., Kaag, Anne Marije, de Vries, Taco J.   +4 more
core   +3 more sources

The Effect of Hunger and Satiety on Mood-Related Food Craving

Frontiers in Psychology, 2020
In addition to hunger, which results from food deprivation, fasting, or restrained eating, food craving is thought to be one of the major factors influencing eating behavior.
Janina Reents, Ann-Kathrin Seidel, Christian Dirk Wiesner, Anya Pedersen   +3 more
doaj   +1 more source

Depicting People in Visual Cues Affects Alcohol Cue Reactivity in Male Alcohol-Dependent Patients

Brain Sciences, 2022
Cue reactivity is often used to study alcohol cues brain responses. Standardized image sets are used, but the effect of viewing people interacting with the alcohol drink remains unclear, which is associated with the factors of alcohol cues that influence
Abdulqawi Alarefi, Xunshi Wang, Rui Tao, Qinqin Rui, Guoqing Gao, Ying Wang, Liangjun Pang, Chialun Liu, Xiaochu Zhang   +8 more
doaj   +1 more source

Cue-Reactivity and Smartphone Dependency

, 2021
Objective: Although Cue-Reactivity was originally developed and used with substance addictions, there has been development and validation of cue-reactivity paradigms with behavioral addictions.
Cederstrom, Collytte
core  

Reactivity to Cannabis Cues in Virtual Reality Environments [PDF]

Journal of Psychoactive Drugs, 2009
Virtual reality (VR) cue environments have been developed and successfully tested in nicotine, cocaine, and alcohol abusers. Aims in the current article include the development and testing of a novel VR cannabis cue reactivity assessment system. It was hypothesized that subjective craving levels and attention to cannabis cues would be higher in VR ...
Patrick S, Bordnick, Hilary L, Copp, Amy, Traylor, Ken M, Graap, Brian L, Carter, Alicia, Walton, Mirtha, Ferrer   +6 more
openaire   +2 more sources

Multimodal Assessment of Smoking cue Reactivity During a Smoking Cue Exposure Task

Clinical EEG and Neuroscience, 2022
Background. Cue-reactivity as a characteristic symptom of substance use disorders (SUD) is highly context dependent. Paradigms with high context validity need to be established for the investigation of underlying neurobiological mechanisms. While craving can be assessed by self-report as one aspect of cue-reactivity (CR), the assessment of biological ...
A.M. Kroczek, B. Schröder, D. Rosenbaum, A. Mühleck, J. Diemer, A. Mühlberger, A. J. Fallgatter, A. Batra, A.-C. Ehlis   +8 more
openaire   +2 more sources