Results 81 to 90 of about 1,321,495 (304)

Cultural-Historical Theory and Social Psychology: A Nexus of Ideas

Вестник Московского университета. Серия 14: Психология
Background. The relevance of the stated topic is determined by two circumstances: the need to determine the main directions of the theoretical and methodological reflection of modern social psychology and the task of explaining the socio-psychological ...
Tahir Yu. Bazarov, Elena P. Belinskaya, Olga A. Tikhomandritskaya   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Developing critical reading skills : a coursebook evaluation study [PDF]

, 2020
The aim of the paper is to discuss the importance of teaching critical reading skills, particularly in a foreign language context. The paper consists of two parts: theoretical and empirical.
Kusiak-Pisowacka, Monika
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A Conceptual Model for Scholarly Research Activity [PDF]

, 2010
This paper presents a conceptual model for scholarly research activity, developed as part of the conceptual modelling work within the ???Preparing DARIAH??? European e-Infrastructures project.
Benardou, Agiatis, Constantopoulos, Panos, Dallas, Costis, Gavrilis, Dimitris   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Dissemination of l. S. Vigotski's cultural-historical theory in Brazil

Культурно-историческая психология
Context and relevance. The article presents brief information on how the works of L. S. Vygotsky and his collaborators arrived and spread in Brazil and data from a survey on the Platform of the National Council for Scientific and Technological
Z. Prestes, E. Tunes, M.T. Beck
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Developing Teaching in the "University Classroom": The Teacher as Researcher when Initiating and Researching Innovations

Outlines, 2011
The teacher’s role in the university classroom has traditionally been to present the syllabus to listening students. In Norway new rules have been introduced for the activity in this classroom. The overarching goal for the teaching is to organize a
May Britt Postholm
doaj  

The history of development of the cultural-historical theory and its contemporary perceptions: answering questions and questioning answers

Вестник Московского университета. Серия 14: Психология
Background. The identification of key periods of development in culturalhistorical theory is not just a task of historical interest. It may help to reconstruct the logics and the moving forces in the development of Vygotsky’s theoretical approaches at ...
Nikolai N. Veresov
doaj   +1 more source