Results 91 to 100 of about 779,176 (289)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

ECONOMIC CONTRIBUTION OF COPYRIGHT-BASED INDUSTRIES AND IMPACT ON EMPLOYMENT AND PERFORMANCE INDICATORS IN KNOWLEDGE-BASED SOCIETY DEVELOPING IN ROMANIA [PDF]

open access: yes
The economic dimension of copyright-based industries sector in Romania is becoming of higher interest, on the one hand, for policy-makers taking into consideration its increasing contribution to GDP, employment, foreign trade and investment and, on the ...
Gheorghe ZAMAN, Valentina VASILE
core  

From audiences to publics : convergence culture and the Harry Potter phenomenon [PDF]

open access: yes, 2014
In the mid-nineties, changing business and communication models influenced the way in which cultural industries operated. The spheres of public and private, production and distribution, ownership and access had to be reconsidered and were characterised ...
Fenech, Giuliana
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Internet Marketing in Cultural Industries: from movie to arts [PDF]

open access: yes
Marketing skills have been developed by firms of several cultural industries for more than three decades. From movie companies to performing arts, from museums to art fairs, every stakeholder has adopted and is going to implement innovative communication
Besana, Angela
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Enhancing political trust through media diversity in post-pandemic China: policy insights for achieving sustainable development goals

open access: yesFrontiers in Communication
IntroductionPolitical trust is essential for achieving the United Nations’ Sustainable Development Goals (SDGs), especially in the context of new media’s impact during health crises.
Ming Wei   +3 more
doaj   +1 more source

Do creative industries cluster? Mapping Creative Local Production Systems in Italy [PDF]

open access: yes
An important debate on the role of creativity and culture as factors of local economic development is distinctly emerging. Despite the emphasis put on the theoretical definition of these concepts, it is necessary to strengthen comparative research for ...
Francesco Capone   +2 more
core  

Home - About - Disclaimer - Privacy