Results 61 to 70 of about 66,987 (261)

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Evaluation and optimization of park cooling benefits based on cumulative impact and landscape pattern

Scientific Reports
City parks can cool the surrounding environment and mitigate the urban heat island (UHI) effect, considerable improving the city’s adaptability to climate.
Yao Xiong, Xinyu Xie, Yunfeng Yang
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Different, different but same? Recreational opportunities and user preferences of inner-city Urban Green Spaces in Hanover and Thessaloniki

Frontiers in Sustainable Cities
Studies on Urban Green Spaces (UGSs) often focus on quantity and/or proximity but lack qualitative assessment, which is particularly important in the case of cross-regional comparisons.
Karlotta Ingmann, Garyfallia Katsavounidou, Nora Mehnen   +2 more
doaj   +1 more source

Cultural Landscape in World Heritage Conservation and Cultural Landscape Conservation Challenges in Asia

Built Heritage, 2018
UNESCO was the first United Nations agency to deal with landscapes at a global scale, notably through the World Heritage Convention. In 1992, Cultural Landscapes’ became a new category on the World Heritage List combining works of nature and of humankind:
Mechtild Rössler, Roland Chih-Hung Lin
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Cultural Literary Landscapes

Crossings: An Undergraduate Arts Journal, 2023
"Challenging Cultural Literary Landscapes: Poetry as Mediation, Experience, and Myth” was originally written for an Italian special topics course on the experiences of Italian-Canadians. This essay covers the Italian diaspora’s representation in Canadian literature with a concentration on the depiction of ethnicity, race, and culture.
openaire   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Toys as Tools for Skill-building and Creativity in Adult Life

Seminar.net, 2015
Previous understandings of adult use of toys are connected with ideas of collecting and hobbying, not playing. This study aims to address toys as play objects employed in imaginative scenarios and as learning devices.
Katriina Heljakka
doaj