Results 81 to 90 of about 21,166 (263)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

La situació lingüística a Ucraïna

Revista de Llengua i Dret - Journal of Language and Law, 1997
More than 100 different ethnic groups coexist in Ukraine. An account of the origins of the Ukrainian language is followed by a description of the five historical regions into which the country is divided, and which have given rise to its present ethnic ...
Iryna Kladiy
doaj  

Natural Language Processing and Iraqi Cultural Texts: Computational Approaches to Translation, Heritage, and Literary Analysis

Iraqi Literary and Cultural Review
Objectives: This article examines how natural language processing can support the study, translation, preservation, and interpretation of Iraqi cultural texts.
Tetyana Panyok
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

An Intuitionistic Fuzzy SWARA-AROMAN Decision-Making Framework for Sports Event Management

IEEE Access
In tackling the intricate challenge of selecting best cities for sports events, our innovative approach, the stepwise weight assessment ratio analysis (SWARA)-alternative ranking order method accounting for two-step normalization (AROMAN) method, merges ...
Lei Hu, Qianyi Yu, Chiranjibe Jana, Vladimir Simic, Bandar Bin-Mohsin   +4 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Artificial Intelligence-Based Music as a Cultural Practice: A Socio-Anthropological Analysis of Creativity, Agency, and Algorithmic Mediation

Edukasia
The integration of artificial intelligence (AI) in music production is growing rapidly and has given rise to debates about creativity, authorship, and the role of human agents in cultural practices.
Buky Wibawa Karya Guna, Diah Fatma Sjoraida, Soni Reffali, Agus Sukarna Dipura, Yuly Hidayah   +4 more
doaj   +1 more source

CULTURE, NORMALITY, AND PERSONALITY CONFLICT [PDF]

American Anthropologist, 1948
openaire   +2 more sources

The Differentiated State of Normal and Malignant Cells or How to Define a “Normal” Cell in Culture [PDF]

, 1981
Publisher Summary This chapter discusses the differentiated state of normal and malignant cells. The first step of cell separation (trypsinization and collagenase treatment), by removing membranous receptors and matrix elements and structures, produces a discontinuity between the cell and its environment.
openaire   +3 more sources