Results 91 to 100 of about 7,922,030 (338)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Bridging Cultures Through Subtitling: A Case Study of "Southland" and Romanian Subtitles [PDF]
English Studies at NBUWith the rise of technology and globalisation, subtitling has become essential for accessibility and cross-cultural communication. This study explores the subtitling strategies employed by Romanian subtitlers in the crime drama series Southland, focusing
Marcela Alina Fărcașiu
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Videomaking. Action-Research Experimentations in Highly Diverse Communities [PDF]
, 2017 The clear, steady, peaceful water of the Caribbean sea, customary depicted in old postcards or in touristic advertises, doesn’t account properly of the turbid tides and waves which are shaking the human and physical landscape of the Lesser Antilles ...
giovanni attili
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Unlocking cultural riches: navigating cultural terms translation in ‘The Treasure’ Egyptian movie
Cogent Arts & HumanitiesThis research Investigates the translation strategies of subtitling culture-terms in (The Treasure)’s Egyptian movie. The study places particular emphasis on a spectrum of cultural references encompassing personal names, geographical locations, culinary ...
Noureldin Mohamed Noureldin Abdelaal
doaj +1 more source
Pseudo-archaeology: The Appropriation and Commercialization of Cultural Heritage [PDF]
, 2013 Heritage can be defined as the use of the past to construct ideas about identity in the present. The past that this definition references is most commonly linked to tangible objects, and therefore archaeological artifacts.
Bassett, Alecia
core +2 more sources
Disney films: reflections of the other and the self [PDF]
, 2007 In the last decade of the 20th century most Disney animated features focused on the depiction of cultural otherness. Despite an apparent interest in spreading the knowledge of distant cultures, these films rely almost exclusively on conventional cultural
Di Giovanni, Elena
core +2 more sources
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source