Results 111 to 120 of about 2,069,023 (306)

\u3cem\u3eMaxim\u3c/em\u3e is a Bully: Making Women the Victim for Male Pleasure [PDF]

open access: yes, 2018
This study analyzes domestic violence discourse in 72 issues of Maxim magazine, an influential and widely circulated publication for young men that is rarely studied because it is not digitally archived or searchable.
Nettleton, Pamela Hill, PhD
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

TRANSLATION OF CULTURE-SPECIFIC REFERENCES IN THE TURKISH TRANSLATION OF SHAKESPEARE’S MACBETH

open access: yesInternational Journal of Language and Translation Studies, 2021
Drama is a literary genre that mirrors the people and society and transfers the human nature and life to the reader or the audience within its own social-cultural structure.
Feride Sümbül
doaj  

To re:make; to re:do; to re:think - Localised design practices in a globalised world [PDF]

open access: yes
To live in a global world is to be constantly aware of our own lives and histories and how they may merge and blend with others. Taking a practitioner-led approach to design, and the production of cultural artifacts, this paper will draw on the author’s ...
Shah, Karen
core  

Intertextuality of C.S. Lewis’ The Last Battle [PDF]

open access: yes, 2014
The Chronicles of Narnia has an established position in the canon of children’s literature. However, what on the surface is a fairy tale involving adventures and magic; with children, kings, talking beasts, and wood spirits as main protagonists; is, in
Zegarlińska, Magdalena
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Why are Lorino and Sireniki so different? Exploring communities through festivals, language use, and subsistence practices in contemporary Chukotka [PDF]

open access: yes, 2013
Thesis (M.A.) University of Alaska Fairbanks, 2013Based on research in Chukotka, Russian Far East, this thesis focuses on the contemporary predicaments of native sports, public festivals, language practices, and marine mammal subsistence in the ...
Yashchenko, Oxana   +1 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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