Results 61 to 70 of about 8,418,026 (404)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Innovation in services: corporate culture and investment banking [PDF]

, 2007
The article discusses service innovation in the investment banking industry. Service industry innovations differ from innovations in industries that produce physical products because they rarely have intellectual property and patent protections. However,
Chatman, Jennifer A., Joyce, Caneel K., Lyons, Richard K.   +2 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Pleasure, profit and pain: Alcohol in New Zealand and the contemporary culture of intoxication [PDF]

, 2013
This book details the rich, complex and often contested role of alcohol in New Zealand society. It explores the three fundamental alcohol rights that continue to fight for dominance of the national drinking culture: the rights of individual drinkers to ...
Campbell, Maxine M., Lyons, Antonia, McEwan, Brett James, Swain, David   +3 more
core   +1 more source

The mythological power of hospitality leaders? : a hermeneutical investigation of their reliance on storytelling [PDF]

, 2010
Aims to explore how senior leaders in the hospitality industry use storytelling to disseminate their vision to employees. To illustrate how hermeneutics can be used as a method for the interpretation of qualitative data in hospitality management research.
Gillespie, Cailein H., O'Gorman, Kevin D.   +1 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Sınırların Metalaştırılması ve Bir Kültür Endüstrisi Örneği Olarak E-Mülteci Oyunu

Tiyatro Eleştirmenliği ve Dramaturji Bölümü Dergisi
Sedef Ecer’in E-Mülteci adlı oyunu göç ve mültecilik kavramlarını sosyal medya ve sosyal medyanın bireyler üzerindeki gücü üzerinden irdeler. Oyun iltica etmek zorunda kalan üç kadının trajedisini Adorno ve Horkheimer’ın tanımladıkları kültür endüstrisi ...
Banu Öğünç
doaj   +1 more source

New Zealand Film Industry: Building Culture and Identity [PDF]

, 2018
Below Australia, as close to the bottom of the populated world as one can go, lies the small country of New Zealand, the true “land down-under.” New Zealand offers close to 103,500 square miles of picturesque and varied landscape, along with a population
Swart, Victoria
core   +1 more source

An Exploration of Poverty in Central Appalachia: Questions of Culture, Industry, and Technology

, 2015
By most government statistical definitions, Central Appalachia is one of the most impoverished regions in the United States. Many of the region's residents are low- income, dependent on government benefits, have high rates of obesity and diabetes, and ...
Cara Robinson
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source