Results 61 to 70 of about 8,891,769 (355)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Application of soilless culture technologies in the modern greenhouse industry – A review

European Journal of Horticultural Science, 2018
Soilless culture systems (SCS) are increasingly adopted as a major technological component in the modern greenhouse industry. The core advantage of soilless culture, frequently referenced to as “hydroponics”, is the independence of the crop from the soil
D. Savvas, N. Gruda
semanticscholar   +1 more source

Sınırların Metalaştırılması ve Bir Kültür Endüstrisi Örneği Olarak E-Mülteci Oyunu

Tiyatro Eleştirmenliği ve Dramaturji Bölümü Dergisi
Sedef Ecer’in E-Mülteci adlı oyunu göç ve mültecilik kavramlarını sosyal medya ve sosyal medyanın bireyler üzerindeki gücü üzerinden irdeler. Oyun iltica etmek zorunda kalan üç kadının trajedisini Adorno ve Horkheimer’ın tanımladıkları kültür endüstrisi ...
Banu Öğünç
doaj   +1 more source

'Thinking of Spain in a flat way:' visiting Spain and Spanish cultural heritage through contemporary Japanese anime [PDF]

, 2017
This article contextualizes the representation of Spain and Spanish culture among Japanese cultural producers, particularly through the production of Japanese commercial animation (commonly named anime).
Hernandez-Perez, Manuel
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Eleştirel Teori Perspektifinden Barbie Filminin Betimsel Analizi

Türkiye Film Araştırmaları Dergisi
Bu araştırmada kültür endüstrisinin en önemli araçlarından biri olan sinemanın üretmiş olduğu metalar ele alınmaktadır. Çalışmanın amacı tüketim toplumunu problem alarak, kitlelerin kültürel ürünler aracılığıyla hegemonya altına alınabildiğini ...
Feyza Karaboğa, Yusuf Adıgüzel
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Open-Mindedness Culture, Knowledge-Sharing, Financial Performance, and Industry 4.0 in SMEs

, 2020
Due to limited resources, the implementation of Industry 4.0 solutions is a big challenge in small- and medium-sized enterprises (SMEs). Therefore, it is important to identify the factors that facilitate such implementation.
Anna Michna, Roman Kmieciak
semanticscholar   +1 more source

Participatory truth between Adorno’s negativity and Gadamer’s play: digital media, the culture industry, and Kantian aesthetic consciousness

Acta Academica
This article investigates the intersection between critical theory and hermeneutics, examining whether Hans-Georg Gadamer’s aesthetic philosophy – especially his critique of Kantian aesthetics – might offer an ontological alternative to the culture ...
William Shaer
doaj   +1 more source