Results 81 to 90 of about 8,891,769 (355)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Quality Culture of Manufacturing Enterprises: A Possible Way to Adaptation to Industry 4.0
The social science, 2019 The concept of Industry 4.0 means a new paradigm of modern manufacturing. This phenomenon requires continuous innovation processes and technological development from each enterprise.
Pavol Durana +4 more
semanticscholar +1 more source
Cahiers d’Études GermaniquesThis article shows the extent to which the work Faust (2017) by German visual artist Anne Imhof utilizes the aesthetic as well as the socio-critical potential of performance, understood as transgression.
Kathrin‑Julie ZENKER
doaj +1 more source
Aquaculture Asia, Vol. 11, No. 2, pp.1-38. April-June 2006 [PDF]
, 2006 Selection of high-health postlarvae: a prerequisite for sustainability of the Indian shrimp industry, by S. Saurabh, V. Kumar, S. Karanth and G. Venkateshwarlu. Nucleotides: novel immunostimulants in aquaculture feed, by P. Kalaimani Arasi, N. Felix.
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
New Zealand culture of intoxication: Local and global influences [PDF]
, 2010 This article shows that attitudes towards and behaviours involving the consumption of alcohol in New Zealand have long been problematic. It provides an historical account of social, economic and legislative factors which have influenced the development ...
Campbell, Maxine M. +2 more
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Structural model of celebrityization and daily life of social network users (case study of Tehrani users of Instagram social network) [PDF]
مطالعات رسانههای نوینToday, the media world and its audiences are experiencing a paradigm shift from an era that was characterized by a one-sided, ideology-driven media industry that favored a one-sided, monologue, and dictatorial approach. In contrast, the digital world and
Azam Velayati +2 more
doaj +1 more source
Willamette Valley Epilogue [PDF]
, 2014 Rusty Gaffney gives a brief overview of the culture of the wine industry in Oregon, focusing on the wineries of the Willamette Valley, in this article from his Prince of Pinot blog, volume 9, issue 42.
Gaffney, William Rusty
core +1 more source
Sunderland Software City: The Impact of a Collaborative Project to Develop the Software Industry within the North East of England [PDF]
This paper uses a case study approach to evaluate the impact of a collaborative initiative within the North East of England which sets out to grow and sustain a software industry, based on the strengths of regional players.
Dunn, D +3 more
core +1 more source