Differentiation-dependent secretion of proangiogenic factors by mesenchymal stem cells. [PDF]
PLoS ONE, 2012 Mesenchymal stem cells (MSCs) are a promising cell population for cell-based bone repair due to their proliferative potential, ability to differentiate into bone-forming osteoblasts, and their secretion of potent trophic factors that stimulate ...
Allison I Hoch +3 more
doaj +1 more source
Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model. [PDF]
, 2017 In vitro experiments are essential to understand biological mechanisms; however, the gap between monolayer tissue culture and human physiology is large, and translation of findings is often poor.
Baar, Keith +2 more
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Lorenzo Milani in our times [PDF]
, 2013 This article pays tribute to one of Europe's foremost critical pedagogues, the Tuscan Don Lorenzo Milani, on the ninetieth anniversary of his birth. It highlights the key moments in his life as priest and educator as well as his pedagogical approach ...
Mayo, Peter
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Jurnal Urologi Indonesia, 2021 Objective: To determine the effect of conditioned medium human Adipose-Derived Mesenchymal Stem Cells (CM-hADMSC) on apoptosis of urothelial bladder cancer cells.
Ari Alauddin Mawdudi +7 more
doaj +1 more source
Formation of functional gap junctions in amniotic fluid-derived stem cells induced by transmembrane co-culture with neonatal rat cardiomyocytes [PDF]
, 2013 Amniotic fluid-derived stem cells (AFSC) have been reported to differentiate into cardiomyocyte-like cells and form gap junctions when directly mixed and cultured with neonatal rat ventricular myocytes (NRVM).
Augustini, Emily +4 more
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Communications Biology, 2021 Rore et al generate testicular somatic cell-like cells (TesLCs) including Sertoli cell-like cells from mouse embryonic stem cells in xeno-free culture. They created testicular organoids in aggregation co-culture of TesLCs and epiblast-like cells (EpiLCs)
Holly Rore +4 more
doaj +1 more source
Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids [PDF]
, 2019 Tissue specific extracellular matrices (ECM) provide structural support and enable access to molecular signals and metabolites, which are essential for directing stem cell renewal and differentiation.
Al-Aama, Jumana +15 more
core +2 more sources
Evidence for regulated interleukin-4 expression in chondrocyte-scaffolds under in vitro inflammatory conditions. [PDF]
PLoS ONE, 2011 OBJECTIVE: To elucidate the anti-inflammatory and anabolic effects of regulated expression of IL-4 in chondrocyte-scaffolds under in vitro inflammatory conditions.
Muhammad Farooq Rai +3 more
doaj +1 more source
Murine Blastocysts Release Mature MicroRNAs Into Culture Media That Reflect Developmental Status
Frontiers in Genetics, 2021 Extracellular microRNA (miRNA) sequences derived from the pre-implantation embryo have attracted interest for their possible contributions to the ongoing embryonic–uterine milieu, as well as their potential for use as accessible biomarkers indicative of ...
David Connor Hawke +11 more
doaj +1 more source
A bioprinted cardiac patch composed of cardiac-specific extracellular matrix and progenitor cells for heart repair [PDF]
, 2018 Congenital heart defects are present in 8 of 1000 newborns and palliative surgical therapy has increased survival. Despite improved outcomes, many children develop reduced cardiac function and heart failure requiring transplantation.
Bejleri, Donald +6 more
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