Results 41 to 50 of about 3,512,085 (357)
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
Gene editing has emerged as a powerful tool for the therapeutic correction of monogenic diseases. CRISPR-Cas9 applied to hematopoietic stem and progenitor cells (HSPCs) has shown great promise in proof-of-principle preclinical studies to treat ...
Rajeev Rai+6 more
doaj
RESPONSES OF SOME NEW ROMANIAN POTATO VARIETIES TO THE IN VITRO HIDRIC STRESS
Plant performance and crop yield are negatively affected by drought and heat in the context of the global climate changes. The present study was carried out to the National Institute for Research and Development Brasov, Romania, to observe the ...
Manuela Hermeziu+2 more
doaj +1 more source
Friables and embryogenic callus induction from embryo, ovule and style of citrus rootstocks : [P97] [PDF]
The incorporation of new technologies such as in vitro selection and protoplast fusion methods into citrus improvement programs offers new opportunities to facilitate, expedite, and fully utilize germplasm variability for both scion and rootstock ...
Arsalan, N.+6 more
core
Bta-miR-10b secreted by bovine embryos negatively impacts preimplantation embryo quality [PDF]
In a previous study, we found miR-10b to be more abundant in a conditioned culture medium of degenerate embryos compared to that of blastocysts. Here, we show that miR-10b mimics added to the culture medium can be taken up by embryos. This uptake results
Deforce, Dieter+6 more
core +1 more source
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg+2 more
wiley +1 more source
Background and Aims: Fibromyalgia (FM) is a chronic pain syndrome affected by the hippocampal function. Mesenchymal stem cells-conditioned medium (MSC-CMs) has shown antioxidant and neuroprotective potentials in treating various diseases.
Farzaneh Jasbinia+1 more
doaj
An exploratory study of mechanisms to transfer and embed a value-based culture : A thesis presented in partial fulfilment of the requirements for the degree of Masters of Business Studies in Management at Massey University, Auckland, New Zealand [PDF]
This exploratory study seeks to build on the work of theorists who have proposed concepts to enhance organisational culture through a better alignment of values.
Wallace, Andrew Mark
core
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
FIBRIN AND SERUM AS A CULTURE MEDIUM [PDF]
A technique is described by which a medium composed of fibrinogen suspension, serum, and embryo juice may be made. Fibroblasts grew in this medium about as well as in plasma and embryo juice. A strain of connective tissue in this medium remained practically as active as the control for several passages.
openaire +3 more sources