Results 31 to 40 of about 19,711 (263)

IDEA-6G: Revolutionizing 6G Networks with Integrated Digital Twin and Self-Healing Mechanisms

Journal of High-Frequency Communication Technologies
6G network is an innovative concept of connectivity, which offers unparalleled speeds, ultralow latency, and extensive device connectivity that surpass the capabilities of the current 5G networks.
Anil Audumbar Pise, Yogesh Khandokar
doaj   +1 more source

Parameterizing convective organization

Journal of Advances in Modeling Earth Systems, 2011
Lateral mixing parameters in buoyancy-driven deep convection schemes are among the most sensitive and important unknowns in atmosphere models. Unfortunately, there is not a true optimum value for plume mixing rate, but rather a dilemma or tradeoff ...
Brian Earle Mapes, Richard Brian Neale
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Effect of Endometriosis on Cumulus ATP, Number of Mitochondria and Oocyte Maturity in Cumulus Oocyte Complex in Mice

Revista Brasileira de Ginecologia e Obstetrícia, 2023
Objective Endometriosis causes a decrease in oocyte quality. However, this mechanism is not fully understood. The present study aimed to analyze the effect of endometriosis on cumulus cell adenosine triphosphate ATP level, the number of mitochondria, and
Muhammad Ardianta Widyanugraha, Widjiati Widjiati, Hendy Hendarto   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

A novel role for Ets4 in axis specification and cell migration in the spider Parasteatoda tepidariorum

eLife, 2017
Organizers play important roles during the embryonic development of many animals. The most famous example is the Spemann organizer that sets up embryonic axes in amphibian embryos.
Matthias Pechmann, Matthew A Benton, Nathan J Kenny, Nico Posnien, Siegfried Roth   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Diverse Cloud Regimes in the Northeast Pacific: Evaluating a Mesoscale NWP Model With Shipborne Observations

Meteorological Applications
As marine clouds play an important role in Earth's radiation budget, it is important that global climate and numerical weather prediction (NWP) models accurately simulate them. These clouds are challenging to represent within models due to the incomplete
Julia M. Simonson, Wayne M. Angevine, Joseph B. Olson, David D. Turner   +3 more
doaj   +1 more source

Convective cloud top vertical velocity estimated from geostationary satellite rapid‐scan measurements

Geophysical Research Letters, 2016
We demonstrate that the rate of development of cumulus clouds, as inferred from the so‐called geostationary satellite “rapid‐scan” measurements, is a good proxy for convective cloud top vertical velocity related to deep convective clouds.
Atsushi Hamada, Yukari N. Takayabu
doaj   +1 more source