Reciprocal Interactions Between Human GV-Oocytes and Cumulus Cells: Effects on GVBD, ROS Production, and AMPK Expression [PDF]
MedicinaBackground and Objectives: The quality of cumulus cells (CCs) is a major determinant of germinal vesicle (GV) oocyte maturation, yet the reciprocal effect of GV oocytes on cumulus cell function remains unclear.
Zhaoqiao Ban +4 more
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Robotic Manipulation of Cumulus–Oocyte Complexes for Cumulus Cell Removal
Applied SciencesThe removal of cumulus cells from cumulus–oocyte complexes is a critical step in clinical in vitro fertilization. Since the oocyte is partially occluded by the surrounding cumulus cells and individual cumulus cells are small in size, it is difficult for ...
Rongan Zhai +4 more
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Multi-omics reveal the metabolic patterns in mouse cumulus cells during oocyte maturation [PDF]
Journal of Ovarian Research, 2023 Bi-directional communication between cumulus cells and the surrounded oocytes is important for the development and functions of both compartments. However, the metabolic framework in cumulus cells has not been systematically described.
Ming Chen +8 more
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Cumulus cells and their extracellular matrix affect the quality of the spermatozoa penetrating the cumulus mass [PDF]
Fertility and Sterility, 2009 To investigate the role of the cumulus cells and the cumulus matrix in affecting the penetrability, morphology, acrosome reaction, and motility of human spermatozoa penetrating the cumulus oophorus.Controlled experimental laboratory study.University gynecology unit.Women undergoing assisted reproduction treatment and men visiting the subfertility ...
Lee Kai-Fai Calvin +2 more
exaly +5 more sources
The beneficial effects of cumulus cells and oocyte-cumulus cell gap junctions depends on oocyte maturation and fertilization methods in mice [PDF]
PeerJ, 2016 Cumulus cells are a group of closely associated granulosa cells that surround and nourish oocytes. Previous studies have shown that cumulus cells contribute to oocyte maturation and fertilization through gap junction communication.
Cheng-Jie Zhou +9 more
doaj +5 more sources
Isolation of Human Cumulus Granulosa Cells
Van Tıp Dergisi, 2022 INTRODUCTION: Follicles are the basic functional units of the ovary. It is characterized by the growth and development of ovarian follicles, proliferation and differentiation of granulosa cells.
Murat Serkant Ünal, Cihan Kabukçu
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Cumulus Cells and their Associations with Immune Functions
Reproductive and Developmental Medicine, 2018 The recent progress in the association of cumulus cells with immune functions is a largely ignored area. With over 350 million new sexually transmitted infections occurring annually in adults of reproductive age, we feel the need to explore more about ...
Ping Xia, Clement Leung-Kwok Chan
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Changes in the transcriptomic profile of cumulus cells under the influence of cumulus-oocytes complex pre-incubation. [PDF]
Sci RepPre-incubation of the cumulus-oocyte complex (COCs) may lead to better function of cumulus cells (CCs) and higher oocyte quality by changing the transcriptomic profile of CCs. 140 cumulus cell samples were isolated from 12 participants and divided into two groups based on pre-incubation time.
Govahi A +6 more
europepmc +4 more sources
Гинекология, 2021 Cumulus cells are essential during oocytes growth and development, as well as during their maturation and fertilization. Research results have shown that embryo co-cultivation with autologous cumulus cells increases the frequency of blastocyst formation,
Gunai R. Asfarova +6 more
doaj +1 more source
Cumulus Cells Are Potential Candidates for Cell Therapy [PDF]
In Vivo, 2019 Cumulus cells (CCs) originate from the membrane granulosa cells and surround oocytes during follicle maturation. CCs produce high levels of hyaluronan that targets CD44, which is a major tumorigenic marker. This study aimed to investigate whether CCs have a role in cell therapy by targeting CD44 in pancreatic cancer cells.CCs were isolated from the ...
Coban, Esra Aydemir +6 more
openaire +3 more sources