Results 21 to 30 of about 16,687 (259)

Biological and physiological characteristics of human cumulus cells in adherent culture condition

open access: yesInternational Journal of Reproductive BioMedicine, 2020
Background: Cumulus cells, as oocyte nurse cells, provide a suitable microenvironment with growth factors and cellular interactions required for oocyte maturation.
Somayyeh Sadat Tahajjodi   +6 more
doaj   +1 more source

Functional signaling and gene regulatory networks between the oocyte and the surrounding cumulus cells

open access: yesBMC Genomics, 2018
Background The maturation and successful acquisition of developmental competence by an oocyte, the female gamete, during folliculogenesis is highly dependent on molecular interactions with somatic cells. Most of the cellular interactions identified, thus
Fernando H. Biase, Katelyn M. Kimble
doaj   +1 more source

Cumulus Cells Block Oocyte Meiotic Resumption via Gap Junctions in Cumulus Oocyte Complexes Subjected to DNA Double-Strand Breaks.

open access: yesPLoS ONE, 2015
During mammalian oocyte growth, genomic DNA may accumulate DNA double-strand breaks (DSBs) induced by factors such as reactive oxygen species. Recent evidence demonstrated that slight DSBs do not activate DNA damage checkpoint proteins in denuded oocytes.
Ming-Hong Sun   +5 more
doaj   +1 more source

The activated DNA double-strand break repair pathway in cumulus cells from aging patients may be used as a convincing predictor of poor outcomes after in vitro fertilization-embryo transfer treatment. [PDF]

open access: yesPLoS ONE, 2018
Women with advanced maternal age exhibit low anti-Müllerian hormone (AMH) levels and an altered follicular environment, which is associated with poor oocyte quality and embryonic developmental potential.
Xu-Lei Sun   +8 more
doaj   +1 more source

Tight gene co-expression in BCB positive cattle oocytes and their surrounding cumulus cells

open access: yesReproductive Biology and Endocrinology, 2022
Background Cytoplasmic and nuclear maturation of oocytes, as well as interaction with the surrounding cumulus cells, are important features relevant to the acquisition of developmental competence.
Bailey N. Walker   +12 more
doaj   +1 more source

Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos

open access: yesPhysiological Genomics, 2014
Cumulus oophorus cells play an essential role in oocyte development. They are also widely employed as donor cells for cloning by somatic cell nuclear transfer. Our previous studies revealed that Cbx4 mRNA was overexpressed in cloned two-cell embryos.
Lanping, Hao   +3 more
openaire   +3 more sources

Effect of androgen substrates on the steroidogenic pattern of cumulus cells: Correlation with cumulus culture morphology [PDF]

open access: yesJournal of Assisted Reproduction and Genetics, 1997
In previous studies, higher progesterone secretion was observed in mature versus immature cumulusoocyte complexes. In mature cumulus mass that become homogeneously spread in culture (type C/D) progesterone secretion was higher than in partially (type B) or totally (type A) aggregated morphology.
S, Bar-Ami, A, Regev, H, Gitay-Goren
openaire   +2 more sources

Effects of oocyte-derived growth factors on the growth of porcine oocytes and oocyte–cumulus cell complexes in vitro

open access: yesThe Journal of Reproduction and Development, 2021
During oocyte growth and follicle development, oocytes closely communicate with cumulus cells. We examined the effects of oocyte-derived growth factors, growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15), on the growth and ...
Riho MORIKAWA, Jibak LEE, Takashi MIYANO
doaj   +1 more source

Protection of cumulus cells following dehydroepiandrosterone supplementation

open access: yesGynecological Endocrinology, 2016
Background: Growing studies have demonstrated that dehydroepiandrosterone (DHEA) may improve fertility outcomes in poor ovarian responders (PORs). The aim of this study was to compare clinical outcomes and cumulus cell (CC) expression before and after DHEA treatment in PORs undergoing in vitro fertilization (IVF) cycles. Methods: Six patients with poor
Li-Te, Lin   +6 more
openaire   +2 more sources

EFFECT OF OOCYTE QUALITY AND CUMULUS CELLS ON MEIOTIC COMPETENCE OF VITRIFIED-THAWED BUFFALO OOCYTES [PDF]

open access: yesAssiut Veterinary Medical Journal, 2020
The work aimed to study the effect of oocytes quality and the presence or removal of cumulus cells on the meiotic competence of vitrified-thawed immature buffalo oocytes.
S.M.A EL-RHEEM   +4 more
doaj   +1 more source

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