Results 41 to 50 of about 16,687 (259)

THE PROLIFERATION OF DOMINANT FOLLICLE CUMULUS CELLS IN IN VITRO CONDITIONS

Zdravniški Vestnik, 2002
Background. We studied the proliferative capacity of dominant follicle cumulus cells under in vitro conditions in natural in vitro fertilization (IVF) cycles.
Mojca Čižek-Sajko, Veljko Vlaisavljević   +1 more
doaj  

Effect of Acrylamide on Oocyte Nuclear Maturation and Cumulus Cells Apoptosis in Mouse In Vitro. [PDF]

PLoS ONE, 2015
Acrylamide (ACR) is a chemical compound with severe neurotoxicity, genotoxicity, carcinogenicity and reproductive toxicity. Recent studies showed that ACR impairs the function of reproductive organs, e.g., epididymis and testes.
Shuzhen Liu, Ligang Jiang, Tao Zhong, Shuhui Kong, Rongbin Zheng, Fengyun Kong, Cong Zhang, Lei Zhang, Liguo An   +8 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Progesterone from the Cumulus Cells Is the Sperm Chemoattractant Secreted by the Rabbit Oocyte Cumulus Complex

PLoS ONE, 2008
La quimiotaxis espermática en mamíferos se ha identificado hacia varias fuentes femeninas como el líquido folicular (FF), el líquido del oviducto y el medio acondicionado del cumulus oophorus (CU) y el ovocito (O). Aunque se confirmaron varias sustancias como quimioatrayentes de espermatozoides, la progesterona (P) parece ser el mejor candidato ...
Héctor Alejandro Guidobaldi, María E. Teves, Diego Rafael Uñates, Agustín Anastasía, Laura C. Giojalas   +4 more
openaire   +4 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Single-cell RNA-seq reveals the effects of the FecB mutation on the transcriptome profile in ovine cumulus cells

Scientific Reports
Genetic variations in the ovine ovulation rate, which are associated with the FecB mutation, provide useful models by which to explore the mechanisms regulating the development of mammalian antral follicles.
Xiaofei Guo, Yi Fang, Rong Liang, Xiangyu Wang, Jinlong Zhang, Chunxiao Dong, Biao Wang, Yu Liu, Mingxing Chu, Xiaoshen Zhang, Rongzhen Zhong   +10 more
doaj   +1 more source

Impact of Prunus Cerasus on PGR and HAS2 in Cumulus Cells and Fertility Outcome [PDF]

Advanced Pharmaceutical Bulletin, 2016
Purpose: Cumulus cells have a critical role in normal oocyte development and fertilization. Prunus cerasus is an anthocyanin rich berry and performs strong antioxidant activity.
Fatemeh Namvar Vansofla, Leila Roshangar, Azadeh Montaseri, Jafar Soleimani Rad   +3 more
doaj   +1 more source

A more accurate analysis of maternal effect genes by siRNA electroporation into mouse oocytes

The Journal of Reproduction and Development, 2023
Maternal RNA and proteins accumulate in mouse oocytes and regulate initial developmental stages. Sperm DNA combines with protamine, which is exchanged after fertilization with maternal histones, including H3.3; however, the effect of H3.3 on development ...
Takuto YAMAMOTO, Shinnosuke HONDA, Issei IDEGUCHI, Motoki SUEMATSU, Shuntaro IKEDA, Naojiro MINAMI   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The Number of LH Receptor could Predict the Success of Oocyte Maturity in the Process of In Vitro Maturation

Indonesian Journal of Obstetrics and Gynecology, 2013
Objective: To evaluate the relationship between the number of LH receptor and the success of oocyte maturity in the process of in vitro maturation (IVM). Method: This experimental study was conducted in the Permata Hati Infertility Clinical Laboratory,
Adek Amansyah, Moch Anwar, Yudha H Febrianto   +2 more
doaj   +1 more source