Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley +1 more source
UJI FLAVONOID KUNYIT PUTIH (Curcuma zedoria) DAN KUNYIT KUNING (Curcuma longa) SEBAGAI SENYAWA ANTIBAKTERI Stahylococcus aureus [PDF]
Introduction: Nosocomial infections are one of the causes of high morbidity and mortality rates in the world, both in developed and developing countries (Kusumayanti, 2017). The prevalence of nosocomial infections in Southeast Asia is 10.0%, the European
Khanifah, Farach
core +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
ABSTRACT Disease outbreaks and the associated reliance on antibiotics pose major constraints to the sustainability of modern aquaculture. As regulatory pressures increase and consumer demand shifts toward residue‐free production, diverse biological interventions are gaining prominence as viable alternatives to chemotherapeutics.
Mustafa Öz +5 more
wiley +1 more source
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL RIMPANG KUNYIT (Curcuma longa L.) TERHADAP Staphylococcus aureus DAN Pseudomonas aeruginosa [PDF]
ABSTRAK Kunyit (Curcuma longa L.) merupakan salah satu jenis tanaman obat yang termasuk dalam keluarga Zingiberaceae. Senyawa aktif yang terkandung dalam rimpang kunyit (Curcuma longa L.) mampu bekerja sebagai antibakteri.
Neni Sri Gunarti +2 more
core +1 more source
Hepatoprotective effect of Curcuma longa against lead induced toxicity in Wistar rats [PDF]
Aim: The present investigation has been conducted to evaluate the hepatoprotective effect of Curcuma longa against lead induced toxicity.Materials and Methods: For this study, 24 Wistar albino rats were taken.
S. L. Baxla +5 more
doaj +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Demethoxylated curcuminoids as antidiabetic complication drug leads – in silicostudies [PDF]
Curcuma longa is used traditionally in the treatment of diabetes and diabetic complications. Aldose Reductase (ALR2) inhibition is a plausible therapeutic strategy against diabetic complications.
Olusegun Samson Ajala +3 more
doaj +2 more sources
The effects of Curcuma longa and curcumin on reproductive systems [PDF]
Abstract Objective. Curcuma longa (C. longa) was used in some countries such as China and India for various medicinal purposes. Curcumin, the active component of C. longa, is commonly used as a coloring agent in foods, drugs, and cosmetics. C. longa and curcumin have been known to act as antioxidant, anti-inflammatory, anti-mutagen, and
Mohebbati R. +2 more
openaire +3 more sources
Photodynamic inactivation increases cell death rate on persistent Staphylococcus aureus
Persistent bacteria have the ability to survive extended periods of antibiotic stress by entering a metabolically dormant state. This study investigated persistence formation in two S. aureus strains and evaluated the effects of PDI using curcumin. Post‐PDI time‐kill assays conducted after metabolic recovery showed a higher rate of bacterial death ...
Maria Vitória Silva Pereira +3 more
wiley +1 more source

