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Curcumin and Cancer [PDF]

open access: yesNutrients, 2019
Curcumin, a polyphenol extracted from Curcuma longa in 1815, has gained attention from scientists worldwide for its biological activities (e.g., antioxidant, anti-inflammatory, antimicrobial, antiviral), among which its anticancer potential has been the ...
A. Giordano, G. Tommonaro
semanticscholar   +5 more sources

Impacts of turmeric and its principal bioactive curcumin on human health: Pharmaceutical, medicinal, and food applications: A comprehensive review

open access: yesFrontiers in Nutrition, 2023
The yellow polyphenolic pigment known as curcumin, originating from the rhizome of the turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as in cooking and food coloring.
M. El‐Saadony   +17 more
semanticscholar   +1 more source

A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin

open access: yesFrontiers in Pharmacology, 2022
Graphical Abstract Curcuma longa Linn. (C. longa), popularly known as turmeric, belongs to the Zingiberaceae family and has a long historical background of having healing properties against many diseases. In Unani and Ayurveda medicine, C. longa has been
S. Fuloria   +16 more
semanticscholar   +1 more source

Anti-Inflammatory Effects of Curcumin in the Inflammatory Diseases: Status, Limitations and Countermeasures

open access: yesDrug Design, Development and Therapy, 2021
Curcumin is a natural compound with great potential for disease treatment. A large number of studies have proved that curcumin has a variety of biological activities, among which anti-inflammatory effect is a significant feature of it.
Ying Peng   +7 more
semanticscholar   +1 more source

Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis

open access: yesCell Death and Differentiation, 2023
Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for prevention and therapy of colorectal cancer/CRC. However, the exact mechanism of action and the downstream mediators of curcumin’s tumor suppressive effects have ...
Chunfeng Liu   +3 more
semanticscholar   +1 more source

Curcumin: Biological Activities and Modern Pharmaceutical Forms

open access: yesAntibiotics, 2022
Curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-hepta-1,6-diene-3,5-dione) is a natural lipophilic polyphenol that exhibits significant pharmacological effects in vitro and in vivo through various mechanisms of action.
Maja Urošević   +5 more
semanticscholar   +1 more source

Curcumin‐piperine co‐supplementation and human health: A comprehensive review of preclinical and clinical studies

open access: yesPhytotherapy Research, 2023
Curcumin is extracted from the rhizomes Curcuma longa L. It is known for its anti‐inflammatory and anti‐oxidant activities. Despite its safety and potential for use against various diseases, curcumin's utility is restricted due to its low oral ...
Hajar Heidari   +5 more
semanticscholar   +1 more source

Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases

open access: yesInflammoPharmacology, 2023
Chemokines belong to the family of cytokines with chemoattractant properties that regulate chemotaxis and leukocyte migration, as well as the induction of angiogenesis and maintenance of hemostasis.
Mahvash Sadeghi   +7 more
semanticscholar   +1 more source

Titanium Dioxide-Curcumin Composite Materials from Aceh Curcuma Natural Source and Their Evaluation as Antiradical Agents Through In Vitro Study

open access: yesIndonesian Journal of Chemistry, 2023
The usage of antiradical agents is pivotal for suppressing the negative effects of free radicals on human health. Curcumin, a well-known natural antiradical agent, suffers from its low stability and high price, thus, limiting its potential in real ...
Indriana Kartini   +4 more
doaj   +1 more source

Comparison of Inhibitory Effect of Curcumin Nanoparticles and Free Curcumin in Human Telomerase Reverse Transcriptase Gene Expression in Breast Cancer [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2013
Purpose: Telomerase is expressed in most cancers, including breast cancer. Curcumin, a polyphenolic compound that obtained from the herb of Curcuma longa, has many anticancer effects. But, its effect is low due to poor water solubility.
Nosratollah Zarghami   +2 more
doaj   +1 more source

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