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Curcumin, a polyphenol extracted from Curcuma longa in 1815, has gained attention from scientists worldwide for its biological activities (e.g., antioxidant, anti-inflammatory, antimicrobial, antiviral), among which its anticancer potential has been the ...
A. Giordano, G. Tommonaro
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The yellow polyphenolic pigment known as curcumin, originating from the rhizome of the turmeric plant Curcuma longa L., has been utilized for ages in ancient medicine, as well as in cooking and food coloring.
M. El‐Saadony +17 more
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Graphical Abstract Curcuma longa Linn. (C. longa), popularly known as turmeric, belongs to the Zingiberaceae family and has a long historical background of having healing properties against many diseases. In Unani and Ayurveda medicine, C. longa has been
S. Fuloria +16 more
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Curcumin is a natural compound with great potential for disease treatment. A large number of studies have proved that curcumin has a variety of biological activities, among which anti-inflammatory effect is a significant feature of it.
Ying Peng +7 more
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Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
Curcumin, a natural phytochemical isolated from tumeric roots, represents a candidate for prevention and therapy of colorectal cancer/CRC. However, the exact mechanism of action and the downstream mediators of curcumin’s tumor suppressive effects have ...
Chunfeng Liu +3 more
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Curcumin: Biological Activities and Modern Pharmaceutical Forms
Curcumin (1,7-bis-(4-hydroxy-3-methoxyphenyl)-hepta-1,6-diene-3,5-dione) is a natural lipophilic polyphenol that exhibits significant pharmacological effects in vitro and in vivo through various mechanisms of action.
Maja Urošević +5 more
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Curcumin is extracted from the rhizomes Curcuma longa L. It is known for its anti‐inflammatory and anti‐oxidant activities. Despite its safety and potential for use against various diseases, curcumin's utility is restricted due to its low oral ...
Hajar Heidari +5 more
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Curcumin and chemokines: mechanism of action and therapeutic potential in inflammatory diseases
Chemokines belong to the family of cytokines with chemoattractant properties that regulate chemotaxis and leukocyte migration, as well as the induction of angiogenesis and maintenance of hemostasis.
Mahvash Sadeghi +7 more
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The usage of antiradical agents is pivotal for suppressing the negative effects of free radicals on human health. Curcumin, a well-known natural antiradical agent, suffers from its low stability and high price, thus, limiting its potential in real ...
Indriana Kartini +4 more
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Comparison of Inhibitory Effect of Curcumin Nanoparticles and Free Curcumin in Human Telomerase Reverse Transcriptase Gene Expression in Breast Cancer [PDF]
Purpose: Telomerase is expressed in most cancers, including breast cancer. Curcumin, a polyphenolic compound that obtained from the herb of Curcuma longa, has many anticancer effects. But, its effect is low due to poor water solubility.
Nosratollah Zarghami +2 more
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