Results 51 to 60 of about 245,137 (370)

A Review of Curcumin and Its Derivatives as Anticancer Agents

open access: yesInternational Journal of Molecular Sciences, 2019
Cancer is the second leading cause of death in the world and one of the major public health problems. Despite the great advances in cancer therapy, the incidence and mortality rates of cancer remain high.
Mhd Anas Tomeh   +2 more
semanticscholar   +1 more source

Curcumin and Endometriosis [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Endometriosis is one of the main common gynecological disorders, which is characterized by the presence of glands and stroma outside the uterine cavity. Some findings have highlighted the main role of inflammation in endometriosis by acting on proliferation, apoptosis and angiogenesis.
Alexandre Vallée, Yves Lecarpentier
openaire   +2 more sources

Curcumin upregulates transforming growth factor-β1, its receptors, and vascular endothelial growth factor expressions in an in vitro human gingival fibroblast wound healing model

open access: yesBMC Oral Health, 2021
Background Curcumin accelerates healing of oral wounds; however, the responsible mechanisms remain underexplored. Our hypothesis is curcumin regulates the expression of wound healing-related genes in human gingival fibroblasts (hGFs).
Auspreeya Rujirachotiwat   +1 more
doaj   +1 more source

Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]

open access: yes, 2017
Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto   +10 more
core   +2 more sources

Bioinformatics study and cytotoxicity of several curcumin analogues in ovarian cancer

open access: yesCurrent Research in Toxicology
Ovarian cancer ranks as Indonesia’s third-leading cause of cancer-related death, emphasising the need for innovative treatments. This study combined bioinformatics, molecular docking, and experimental assays to tackle this challenge.
Retno Murwanti   +5 more
doaj   +1 more source

On the properties of a single OPLS-UA model curcumin molecule in water, methanol and dimethyl sulfoxide. Molecular dynamics computer simulation results [PDF]

open access: yes, 2017
The properties of model solutions consisting of a solute --- single curcumin molecule in water, methanol and dimethyl sulfoxide solvents have been studied using molecular dynamics (MD) computer simulations in the isobaric-isothermal ensemble.
Ilnytskyi, J. M.   +2 more
core   +2 more sources

Enhancing the Bioavailability and Bioactivity of Curcumin for Disease Prevention and Treatment

open access: yesAntioxidants
Curcumin, a natural polyphenolic component from Curcuma longa roots, is the main bioactive component of turmeric spice and has gained increasing interest due to its proposed anti-cancer, anti-obesity, anti-inflammatory, antioxidant, and lipid-lowering ...
C. Bertoncini-Silva   +5 more
semanticscholar   +1 more source

Curcumin: Biological, Pharmaceutical, Nutraceutical, and Analytical Aspects

open access: yesMolecules, 2019
Turmeric is a curry spice that originated from India, which has attracted great interest in recent decades because it contains bioactive curcuminoids (curcumin, demethoxycurcumin, and bisdemethoxycurcumin).
Raghavendhar R. Kotha   +1 more
semanticscholar   +1 more source

Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women

open access: yesArtery Research, 2012
Background: Reduction in arterial compliance with aging increases the risk of cardiovascular disease. Lifestyle modification, particularly aerobic exercise and dietary modification, has a favorable effect on vascular aging. Curcumin, a major component of
Nobuhiko Akazawa   +6 more
doaj   +1 more source

The potential for dietary factors to prevent or treat osteoarthritis [PDF]

open access: yes, 2014
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease-modifying drugs. It is a leading cause of disability in the UK. Increasing age and obesity are both major risk factors for OA and the health and economic burden of this ...
Bao, Yongping   +8 more
core   +1 more source

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