Results 61 to 70 of about 77,357 (230)
Advanced Robotics Research, EarlyView.An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma +10 more
wiley +1 more source
A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
Advanced Science, EarlyView.We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source
The Stability, Sustained Release and Cellular Antioxidant Activity of Curcumin Nanoliposomes
Molecules, 2015 Curcumin is a multifunctional and natural agent considered to be pharmacologically safe. However, its application in the food and medical industry is greatly limited by its poor water solubility, physicochemical instability and inadequate bioavailability.
Xing Chen +5 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai +6 more
wiley +1 more source
Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System
Bioinorganic Chemistry and Applications, 2010 The purpose of present study was to stabilize curcumin food pigment by its complexation with divalent ions like (Zn2+,Cu2+,Mg2+,Se2+), in “green media” and evaluate its stability in vitro compared to curcumin alone.
Bachar Zebib +2 more
doaj +1 more source
ALSUntangled 44: curcumin [PDF]
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2018 ALSUntangled reviews alternative therapies are presented on behalf of persons with ALS (PALS). Here we review the use of curcumin for ALS, for which we have had over 100 requests (1).
openaire +2 more sources
Advanced Science, EarlyView.Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin +12 more
wiley +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Pharmaceutics, 2019 Previously, we synthesized curcumin and a succinate ester prodrug of curcumin namely curcumin diethyl disuccinate (CurDD) in the lab scale, which yielded hundred milligrams to few grams of the compounds.
Chawanphat Muangnoi +7 more
doaj +1 more source
Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics
Advanced Science, EarlyView.This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu +6 more
wiley +1 more source