Results 71 to 80 of about 245,137 (370)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]

open access: yes, 2016
Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V   +7 more
core   +5 more sources

Phytochemical Compounds and Protection from Cardiovascular Diseasesa. A State of the Art [PDF]

open access: yes, 2015
Cardiovascular diseases represent a worldwide relevant socioeconomical problem. Cardiovascular disease prevention relies also on lifestyle changes, including dietary habits.
PAGLIARO, BENIAMINO ROSARIO   +3 more
core   +4 more sources

Curcumin, a Natural Antimicrobial Agent with Strain-Specific Activity

open access: yesPharmaceuticals, 2020
Curcumin, a principal bioactive substance of turmeric (Curcuma longa L.), is reported as a strong antioxidant, anti-inflammatory, antibacterial, antifungal, and antiviral agent.
A. Adamczak   +2 more
semanticscholar   +1 more source

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

Drug-Drug/Drug-Excipient Compatibility Studies on Curcumin using Non-Thermal Methods

open access: yesAdvanced Pharmaceutical Bulletin, 2014
Purpose: Curcumin is a hydrophobic polyphenol isolated from dried rhizome of turmeric. Clinical usefulness of curcumin in the treatment of cancer is limited due to poor aqueous solubility, hydrolytic degradation, metabolism, and poor oral bioavailability.
Moorthi Chidambaram   +1 more
doaj   +1 more source

Clinical effects of curcumin in enhancing cancer therapy: A systematic review

open access: yesBMC Cancer, 2020
Curcumin is herbal compound that has been shown to have anti-cancer effects in pre-clinical and clinical studies. The anti-cancer effects of curcumin include inhibiting the carcinogenesis, inhibiting angiogenesis, and inhibiting tumour growth. This study
K. Mansouri   +7 more
semanticscholar   +1 more source

pH‐Tunable Material Properties of Glycine‐Rich Condensates from Tick Bioadhesive

open access: yesAdvanced Functional Materials, EarlyView.
This work studies the influence of pH on the phase separation behavior of a disordered glycine‐rich protein found in tick bioadhesive. The results show profound impact on the propensity of coacervation, condensate microstructure and viscosity, amphiphilicity of the peptides, and effective encapsulation of therapeutic molecules.
Manali Nandy   +5 more
wiley   +1 more source

Synthesis of Metal–Curcumin Complex Compounds (M = Na⁺, Mg²⁺, Cu²⁺)

open access: yesJurnal Kimia Sains dan Aplikasi, 2020
Curcumin complex compound, MLn (L = curcumin; M = Na+, Mg2+, Cu2+) has been synthesized from the reaction between curcumin and metal precursors (NaCl, MgSO4.7H2O, CuCl2.2H2O) in ethanol under reflux conditions.
Peni Peni   +2 more
doaj   +1 more source

Purification of Curcumin from Ternary Extract-Similar Mixtures of Curcuminoids in a Single Crystallization Step

open access: yes, 2020
Crystallization-based separation of curcumin from ternary mixtures of curcuminoids having compositions comparable to commercial extracts was studied experimentally.
Horosanskaia, E.   +3 more
core   +1 more source

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