Results 81 to 90 of about 5,036,649 (295)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Simulation of a single-phase active power filter based ANN controller [PDF]
, 2013 This project presents the employment of a single-phase active power filter (APF) to compensate harmonics generated by battery charger. The presence of the harmonics leads to various problems and poor power quality.
Mahadan, Mohd Ezwan
core
Symmetric M-ary phase discrimination using quantum-optical probe states
, 2012 We present a theoretical study of minimum error probability discrimination, using quantum- optical probe states, of M optical phase shifts situated symmetrically on the unit circle.
A. S. Holevo +13 more
core +1 more source
Electronic error compensation of a current transformer
Electronics Letters, 1971 A scheme is presented employing two precision resistors and an electronic amplifier for reducing the ratio and phase-angle errors in a current transformer. The amplifier supplies only the error current. The proposed arrangement facilitates the adaptability of inexpensive low ampere-turn c.t.s for calibration work in the laboratory.
P. Sankaran, V.G.K. Murti
openaire +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
, 1965 Time and frequency domain convergence properties of causal and Current Iteration Tracking Error (CITE) discrete time Iterative Learning Control (ILC) algorithms are discussed.
Gunnarsson, Svante, Norrlöf, Mikael
core +1 more source
A comprehensive radial velocity error budget for next generation Doppler spectrometers
, 2016 We describe a detailed radial velocity error budget for the NASA-NSF Extreme Precision Doppler Spectrometer instrument concept NEID (NN-explore Exoplanet Investigations with Doppler spectroscopy).
Bender, Chad +16 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Приборы и методы измерений, 2017 In carrying out eddy current thickness measurement of two-layer conductive objects one from the interfering factors is the presence of variations in the value of the electrical conductivity of the material of the upper layer (coating) when moving from ...
A. V. Chernyshev
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source