Results 71 to 80 of about 5,036,649 (295)

Interplay between Coulomb Blockade and Resonant Tunneling studied by the Keldysh Green's Function Method

open access: yes, 1999
A theory of tunneling through a quantum dot is presented which enables us to study combined effects of Coulomb blockade and discrete energy spectrum of the dot.
A. Groshev   +16 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Comparison of Current Ratio Errors of Support and Toroidal Type CTs in Electric Power Systems: A Case Study

open access: yesIEEE Access
A current transformer (CT) is a specialized device used to reduce high current values to safe and manageable levels in measurement and protection systems. Current ratio error (CRE) is an inevitable error in CTs due to factors such as magnetic saturation,
Ishak Ozer, Ali Unluturk
doaj   +1 more source

Error and Threat Detection: A Review and Evaluation of Current Literature

open access: yesJournal of Aviation/Aerospace Education & Research, 2004
The present project provides a comprehensive review of the literature related to threat and error detection. Although there are current models for understanding the concepts of error and threat, little is known about how individuals detect errors and ...
Christina Frederick-Recascino   +1 more
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

ERROR ELIMINATION FOR CURRENT CONTROL LOOP FOR MULTI-FUNCTIONAL SINGLE-PHASE GRID-CONNECTED INVERTER

open access: yesElectrical engineering & Electromechanics, 2019
Purpose. Elimination of the error of the inverter current control loop by improving its structure and justifying the parameters, which will ensure compliance with the current quality standard at the common coupling to the distribution grid of the load ...
О. О Shavelkin   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Prediction Error Analysis of Finite-Control-Set Model Predictive Current Control for IPMSMs

open access: yesEnergies, 2018
Finite-control-set model predictive current control (FCS-MPCC) has been widely investigated in the field of motor control. When the discrete motor prediction model is not obtained accurately, prediction error often occurs, which can result in improper ...
Jian Li   +5 more
doaj   +1 more source

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