Results 71 to 80 of about 2,556,195 (340)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The development of a curriculum framework for the National Dual Training System (NDTS) in Malaysia [PDF]
, 2013 Curriculum is one of the most important elements in the Technical Education and Vocational Training system. Nonetheless, the existing National Occupational Skill Standard (NOSS)-based curriculum was found incapable of playing this role for its ...
Abu Bakar, Mohd Yusof
core
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Journal of Humanities and Social Sciences Mahasarakham University, 2023 This research aimed to. - 1. Study the current condition and synthesize the science experiential skills of early childhood teachers 2. Develop a model for enhancing the science experiential skills of early childhood teachers of primary school teachers. 3.
Sirithai Thanopajai +2 more
doaj
KWL Plus Learning Management for Improving Mathayomsuksa 3 Students’ Analytical Reading [PDF]
Journal of Humanities and Social Sciences Mahasarakham University, 2022 The purposes of the current study were.-1) to developa KWL Plus learning management with an efficiency of 75/75 for improving Mathayomsuksa 3 students’ analytical reading, 2) to compare the students’ analytical reading before and after learning with the ...
Maliwan suranit, Autthapon Inthasena
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Development of Reading Comprehension Ability of Pratomsuksa 3 Students using SQ4R Integrated with Mind Mapping Learning Management [PDF]
Journal of Humanities and Social Sciences Mahasarakham University, 2022 The purposes of the study were. -1) to develop an SQ4R integrated with mind mapping learning management with an efficiency of 75/75 for Pratomsuksa 3 students, 2) to study reading comprehension ability of students learning with developed learning ...
Warawan Nansathit, Autthapon Inthasena
doaj
Learning from contemporary student activism: towards a curriculum of fervent concern and critical hope [PDF]
, 2020 Eve Mayes, Roger Holdsworth
openalex +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Principles in Patterns (PiP) : Project Evaluation Synthesis [PDF]
, 2012 Evaluation activity found the technology-supported approach to curriculum design and approval developed by PiP to demonstrate high levels of user acceptance, promote improvements to the quality of curriculum designs, render more transparent and efficient
Macgregor, George
core