Results 51 to 60 of about 1,954,048 (306)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Institutional factors and curriculum fidelity in vocational training centres in Kampala City, Uganda
Interdisciplinary Journal of Education Research, 2023 The subject of curriculum fidelity continues to be a crucial area of investigation to uncover how the responsible stakeholders implement the curricula developed in relation to their intended purpose.
Richard Ochwo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Internationalizing the Academic Leadership Curriculum
New Directions for Student LeadershipABSTRACTLeadership educators have a responsibility for preparing students for a global era through an understanding of the global dimensions of leadership. For students to truly understand global dimensions of leadership, an intentional internationalization of leadership curriculum is required.
Evan Witt, Margaret Harris
openaire +2 more sources
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Futures-focused leadership in New Zealand secondary schools [PDF]
, 2009 This study explores the issues facing twenty-first century secondary school principals as they face changes in education brought about by the New Zealand Curriculum, and changes in their communities in the face of the emerging knowledge society.
Hayes, Juliette
core
, 2021 Sweden, as a country based on extremely high secular and self-expression values, serve as an example that somewhat differ from other countries internationally, when it comes to educational leadership curriculum.
Ulrika Haake, Haake, Ulrika,
core +1 more source
Determining the Accuracy of Body Mass Index: Body Composition Using Bioelectrical Impedance Analysis (BIA) [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2015 Background: Body Mass Index (BMI) is commonly used to determine overweightness and obesity in epidemiological studies regardless of the sex and age of the subjects.
Alireza Shahab Jahanlou +1 more
doaj
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
The association between school climate, teacher emotions, and adaptive instruction
Frontiers in EducationIntroductionAlthough adaptive instruction has become increasingly important as a component of effective instruction, the mechanism of adaptive instruction remains underexplored.
Masoumeh Kouhsari +3 more
doaj +1 more source