Results 61 to 70 of about 1,954,048 (306)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Leadership Programs, Discourses, and Participants’ True Sense of Self [PDF]
, 2019 As the challenges communities and organizations face become increasingly complex and interconnected, leadership has continued to evolve to meet these new needs.
Cletzer, D. Adam +2 more
core
Curriculum and Leadership in Transnational Reform Policy: A Discursive-Institutionalist Approach
, 2017 Following an institutional-discursive approach, it is argued in this chapter that the ways in which social and educational questions become intertwined in actual reforms are dependent on cognitive and normative ideas in the public sphere.
Wahlström, Ninni, +3 more
core +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Studying Leadership as Praxis: Experience With a Worldwide Education System
, 2020 Leadership scholars have called for public leadership research to go beyond the traditional case study method, yet there is limited guidance on how to enact such research.
Coartney, Jama S. +4 more
core
, 2023 The article reports on the findings of a qualitative inquiry involving a sample of nine (9) teachers (three participants per school) drawn from three schools within the locality of three education circuits of Emalahleni in Mpumalanga Province (South ...
Nkambule, Bongani Innocent +1 more
core +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
UMT Education Review, 2020 The research was conducted in the positivist paradigm to determine the interactive effect of school principals' leadership style and the teaching characteristics (traditional Vs. Progressive) of school teachers on curriculum implementation.
Seema Arif +2 more
doaj +1 more source