The Curtius rearrangement: mechanistic insight and recent applications in natural product syntheses [PDF]
Organic and Biomolecular Chemistry, 2018 An extensive review on the Curtius reaction and its recent applications in the synthesis of bioactive natural products are reported.
Arun K Ghosh +2 more
exaly +10 more sources
The Curtius Rearrangement: Applications in Modern Drug Discovery and Medicinal Chemistry. [PDF]
ChemMedChem, 2018 AbstractThe Curtius rearrangement is the thermal decomposition of an acyl azide derived from carboxylic acid to produce an isocyanate as the initial product. The isocyanate can undergo further reactions to provide amines and their derivatives. Due to its tolerance for a large variety of functional groups and complete retention of stereochemistry during
Ghosh AK, Brindisi M, Sarkar A.
europepmc +10 more sources
Photoinduced, Copper-Catalyzed Decarboxylative C–N Coupling to Generate Protected Amines: An Alternative to the Curtius Rearrangement [PDF]
Journal of the American Chemical Society, 2017 Wei Zhao, Jonas C Peters, Gregory C Fu
exaly +5 more sources
N-Acylbenzotriazoles as Proficient Substrates for an Easy Access to Ureas, Acylureas, Carbamates, and Thiocarbamates via Curtius Rearrangement Using Diphenylphosphoryl Azide (DPPA) as Azide Donor [PDF]
Synthesis, 2021 A diverse range of ureas, N-acylureas, carbamates, and thiocarbamates has been synthesized in good to excellent yields by reacting N-acylbenzotriazoles individually with amines or amides or phenols or thiols in the presence of diphenylphosphoryl azide ...
Vinod K Tiwari
exaly +3 more sources
Pyridone Annulation via Tandem Curtius Rearrangement/6π-Electrocyclization: Total Synthesis of (−)-Lyconadin C [PDF]
Organic Letters, 2013 Xiayun Cheng, Stephen P Waters
exaly +5 more sources
Oxidative N−N Bond Formation Versus the Curtius Rearrangement
Chemistry – A European JournalAbstractThe oxidative formation of N−N bonds from primary amides has been recently reported and then retracted in the journal Nature Communications by Kathiravan, Nicholls, and co‐authors, utilizing a hypervalent iodane reagent. Unfortunately, the authors failed to recognize the Curtius reaction taking place under the described reaction conditions ...
Melissa Hohenadel +3 more
semanticscholar +5 more sources
Phys Chem Chem PhysThe Curtius and the Wolff rearrangement reactions are investigated in the gas phase by tandem mass spectrometry (MS) and infrared ion spectroscopy (IRIS), probing the nature and intrinsic reactivity of three acyl azides and of one α-diazo keto analyte ...
Harnying W +8 more
europepmc +3 more sources
Curtius Rearrangement of Aromatic Carboxylic Acids to Access Protected Anilines and Aromatic Ureas [PDF]
Organic Letters, 2006 AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Helene Lebel
exaly +6 more sources
An efficient new method for the synthesis of 3-[18 F]fluoro-4-aminopyridine via Yamada-Curtius rearrangement. [PDF]
J Labelled Comp Radiopharm, 2018 Basuli F +4 more
europepmc +4 more sources
Boc-protected 1-(3-oxocycloalkyl)ureas via a one-step Curtius rearrangement: mechanism and scope. [PDF]
Tetrahedron Lett, 2014 Sun X +5 more
europepmc +5 more sources