Results 31 to 40 of about 265,896 (190)

Deconstructive Radical-Radical Coupling for Programmable Remote Acylation. [PDF]

Angew Chem Int Ed Engl
A unified approach to access a variety of 1,n‐dicarbonyls through a radical‐promoted deconstructive process utilizing dual photocatalysis/carbene catalysis is reported. The utility of this strategy is demonstrated with a broad scope with robust functional group tolerance along with application in the preparation of γ‐amino esters, three‐component ...
Cao J, Schull CR, Scheidt KA.
europepmc   +3 more sources

Application of the Curtius rearrangement to the synthesis of 1′-aminoferrocene-1-carboxylic acid derivatives

, 2018
W. Erb, Gael Levanen, T. Roisnel, V. Dorcet   +3 more
semanticscholar   +3 more sources

Novel Sulfur-Containing Polyurethanes using 5-(Chloromethyl)Furfural as a Renewable Building Block. [PDF]

ChemSusChem
A novel methodology is presented for synthesizing biomass‐derived diols using 5‐(chloromethyl)furfural, thiols, and mild reaction conditions. These innovative diols are subsequently utilized in the production of new polyurethanes via polyaddition with both commercially available and biomass‐derived diisocyanates.
Mora Vargas JA, Ribeiro da Silva J, Lancarovici Alves AC, Gómez Higuita GD, Carvalho AJF, Burtoloso ACB.   +5 more
europepmc   +2 more sources

Total Synthesis of Isodaphlongamine H by Iridium-Catalyzed Reductive [3 + 2] Cycloaddition of N-Hydroxylactam. [PDF]

Angew Chem Int Ed Engl
The total synthesis of isodaphlongamine H was accomplished by a lactam strategy. This strategy started with alkylation and N‐oxidation of a readily available chiral lactam. For the key functionalization of the amide carbonyl, an iridium‐catalyzed reductive [3 + 2] cycloaddition of the N‐hydroxylactam afforded the tricyclic isoxazolidine, which was ...
Iwamoto S, Nakano R, Sasaki K, Kobayashi S, Taira Y, Takei K, Kawakita R, Tokuyama A, Nakamura H, Tomoike M, Kawahara R, Murase A, Simizu S, Chida N, Okamura T, Sato T.   +15 more
europepmc   +3 more sources

Strategy-Level Prodrug Synthesis. [PDF]

Chemistry
Prodrug approaches can be expanded by increasing options for controlling site‐selective functionalization, boosting the range of linking groups, and enhancing the chemoselectivity of reactive group incorporation. This Concept describes strategy‐level prodrug synthesis, whereby these issues are addressed at an early stage of a sequence.
Geaneotes PJ, Floreancig PE.
europepmc   +2 more sources

A theoretical study of the thermal Curtius rearrangement of some cinnamoyl azides using the DFT approach [PDF]

Journal of Structural Chemistry, 2015
R. Abu-Eittah, W. Hassan, W. Zordok
semanticscholar   +2 more sources

Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study

Pharmaceuticals, 2023
On the basis of previous reports, novel 2-benzoylhydrazine-1-carboxamides were designed as potential inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Inhibitors of these enzymes have many clinical applications.
Neto-Honorius Houngbedji, Šárka Štěpánková, Václav Pflégr, Katarína Svrčková, Markéta Švarcová, Jarmila Vinšová, Martin Krátký   +6 more
doaj   +1 more source

Novel N-benzyl-2-oxo-1,2-dihydrofuro [3,4-d]pyrimidine-3(4H)-carboxamide as anticancer agent: Synthesis, drug-likeness, ADMET profile, DFT and molecular modelling against EGFR target

Heliyon, 2023
A novel compound N-benzyl-2-oxo-1,2-dihydrofuro [3,4-d]pyrimidine-3(4H)-carboxamide (DHFP) was synthesized by addition, rearrangement, and intramolecular cyclization reactions.
Ayşen Şuekinci Yılmaz, Gühergül Uluçam   +1 more
doaj   +1 more source

One-pot non-isocyanate urethane synthesis via visible light-activated Curtius rearrangement

European Polymer Journal
Vu Thi Tuyet Thuy, Saibal Jana, Wolfgang Wenzel, Patrick Théato, Azra Kocaarslan   +4 more
semanticscholar   +2 more sources

SmI₂-Catalyzed Coupling of Alkyl Housane Ketones and Alkenes in an Approach to Norbornanes. [PDF]

Angew Chem Int Ed Engl
Samarium diiodide (Sml2) is an effective catalyst for the mild, atom‐economical coupling of bicyclo[2.1.0]pentane, or housane, ketones, and electron‐deficient alkenes to give functionalized norbornane structural motifs not easily accessible by classical cycloaddition approaches.
Roy D, Mansell JI, Barison G, Yu S, Katavic R, Romano C, Kaltsoyannis N, Procter DJ.   +7 more
europepmc   +2 more sources