Results 61 to 70 of about 265,896 (190)

Recyclable Dynamic Covalent Networks Derived from Isocyanate Chemistry: The Critical Role of Electronic and Steric Effects in Reversibility

open access: yesChemSusChem, Volume 18, Issue 13, July 1, 2025.
The emergence of dynamic covalent networks, featuring dynamic covalent bonds formed through isocyanate‐involved chemistry, aims to substitute conventional, non‐recyclable polyurethanes and polyureas. The review examines the reversibility of these dynamic bonds and the relevant polymer networks from the lens of electronic and steric influences.The ...
Zhiyong Liu, Youwei Ma
wiley   +1 more source

Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase

open access: yesPest Management Science, Volume 81, Issue 7, Page 3956-3983, July 2025.
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier   +26 more
wiley   +1 more source

N‐ to C‐Peptide Synthesis, Arguably the Future for Sustainable Production

open access: yesJournal of Peptide Science, Volume 31, Issue 6, June 2025.
The advent of epimerization‐free methods for coupling in N‐ to C‐direction synthesis offers improved atom economy for sustainable peptide synthesis. ABSTRACT A revolution in peptide production arrived from the innovation of carboxylate to amine C‐ to N‐direction solid‐phase synthesis.
Kinshuk Ghosh, William D. Lubell
wiley   +1 more source

Proximal and Remote Hydrocarboxylation of Alkenes with Carbon Dioxide Enabled by Nickel‐Catalyzed Hydrogen Atom Transfer

open access: yesAngewandte Chemie, Volume 137, Issue 22, May 26, 2025.
The use of carbon dioxide and alkenes as feedstocks for the production of carboxylic acids holds great significance in sustainable chemistry. Herein, we introduce a simple and unifying nickel‐catalyzed radical hydrocarboxylation for both functionalized and unactivated alkenes at proximal and remote sites.
Rong‐De He, Yixin Lu
wiley   +1 more source

Synthetic Approaches to α-, β-, γ-, and δ-lycoranes. [PDF]

open access: yesEuropean J Org Chem, 2023
Bautista DD   +3 more
europepmc   +1 more source

[2]-Ladderanes as isosteres for meta-substituted aromatic rings and rigidified cyclohexanes. [PDF]

open access: yesNat Commun, 2022
Epplin RC   +10 more
europepmc   +1 more source

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