The emergence of dynamic covalent networks, featuring dynamic covalent bonds formed through isocyanate‐involved chemistry, aims to substitute conventional, non‐recyclable polyurethanes and polyureas. The review examines the reversibility of these dynamic bonds and the relevant polymer networks from the lens of electronic and steric influences.The ...
Zhiyong Liu, Youwei Ma
wiley +1 more source
Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier +26 more
wiley +1 more source
N‐ to C‐Peptide Synthesis, Arguably the Future for Sustainable Production
The advent of epimerization‐free methods for coupling in N‐ to C‐direction synthesis offers improved atom economy for sustainable peptide synthesis. ABSTRACT A revolution in peptide production arrived from the innovation of carboxylate to amine C‐ to N‐direction solid‐phase synthesis.
Kinshuk Ghosh, William D. Lubell
wiley +1 more source
The use of carbon dioxide and alkenes as feedstocks for the production of carboxylic acids holds great significance in sustainable chemistry. Herein, we introduce a simple and unifying nickel‐catalyzed radical hydrocarboxylation for both functionalized and unactivated alkenes at proximal and remote sites.
Rong‐De He, Yixin Lu
wiley +1 more source
A practical synthesis of enantiopure N-carbobenzyloxy-N′-phthaloyl-cis-1,2-cyclohexanediamine by asymmetric reductive amination and the Curtius rearrangement [PDF]
Jun‐ichi Matsuo +4 more
openalex +1 more source
Synthesis of Substituted Benzoxazolinones by the Curtius Rearrangement: Crystal Structures of Intermediates and By-Products [PDF]
Gerhard Laus +4 more
openalex +1 more source
MILD AND EFFICIENT ONE-POT CURTIUS REARRANGEMENT: PREPARATION OF N-tert-BUTYL ADAMANTANYL-1-YL-CARBAMATE [PDF]
openalex +1 more source
Synthesis of dienes from pyrrolidines using skeletal modification. [PDF]
Qin H, Guo T, Lin K, Li G, Lu H.
europepmc +1 more source
Synthetic Approaches to α-, β-, γ-, and δ-lycoranes. [PDF]
Bautista DD +3 more
europepmc +1 more source
[2]-Ladderanes as isosteres for meta-substituted aromatic rings and rigidified cyclohexanes. [PDF]
Epplin RC +10 more
europepmc +1 more source

