Scheme 1 - Curtius rearrangement literature conditions
, 2016 Andrew Marsh +2 more
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ChemSusChem, Volume 18, Issue 13, July 1, 2025.The emergence of dynamic covalent networks, featuring dynamic covalent bonds formed through isocyanate‐involved chemistry, aims to substitute conventional, non‐recyclable polyurethanes and polyureas. The review examines the reversibility of these dynamic bonds and the relevant polymer networks from the lens of electronic and steric influences.The ...
Zhiyong Liu, Youwei Ma
wiley +1 more source
Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase
Pest Management Science, Volume 81, Issue 7, Page 3956-3983, July 2025.The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier +26 more
wiley +1 more source
Enantioselective Synthesis of Dual Serotonergic Azanoradamantane SC-52491 [PDF]
, 1999 A racemic synthesis of azanoradamantane (±)-3 was accomplished via Yamamoto\u27s MAD-catalyzed Diels-Alder protocol. Subsequently, a scalable asymmetric synthesis of azanoradamantane benzamide SC-52491 was carried out employing Helmchen\u27s asymmetric ...
Becker, Daniel +3 more
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The Medicinal Chemistry of Imidazotetrazine Prodrugs [PDF]
, 2014 YesTemozolomide (TMZ) is the standard first line treatment for malignant glioma, reaching “blockbuster” status in 2010, yet it remains the only drug in its class.
Moody, Catherine L. +1 more
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Nachweis von 4-Homocubyl-Carbenium-Ionen als reaktive Zwischenstufen [PDF]
, 1983 Bei der Thermolyse von N-(4-Homocubyl)-N-nitrosoacetamid (9) und bei der Solvolyse von 4-Homocubylbromid (5) in Hexafluor-2-propanol entsteht 4-(Hexafluorisopropoxy)homocuban (6) als Hauptprodukt. Dies beweist das Auftrete von 4-Homocubyl-Carbenium-Ionen
Allard +27 more
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Intramolecular amidocyclopropanation reactions using diethoxymethyl-functionalised lactams as organozinc carbenoid precursors [PDF]
, 2009 Intramolecular amidocyclopropanation reactions of diethoxymethyl-lactams containing a pendant alkene were examined using zinc/TMSCI. With a range of 4-6-membered lactams, bicyclic amidocyclopropanes were obtained with very high diastereoselectivity with ...
Aliev, AE +3 more
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Efficient click-addition sequence for polymer–polymer couplings [PDF]
, 2016 Controlled radical polymerization methods and click chemistry form a versatile toolbox for creating complex polymer architectures. However, the incompatibility between the functional groups required for click reactions and the reaction conditions of ...
Brendel, Johannes C. +2 more
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Hyphenating the curtius rearrangement with Morita-Baylis-Hillman adducts: synthesis of biologically active acyloins and vicinal aminoalcohols [PDF]
, 2011 Giovanni W. Amarante +2 more
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Изучение реакции циклоприсоединения алкилазидов к эпоксиенонам [PDF]
, 2011 Изучены реакции 1,3-диполярного циклоприсоединения 3-арил-1-(2-метилоксиранил)проп2-ен-1-онов с бензил и бутилазидами. Показано, что данное взаимодействие при нагревании региоселективно приводит к образованию нестабильного ...
Асадчий, Николай Борисович +2 more
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