Results 31 to 40 of about 591,277 (274)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Simultaneous Curvature and Temperature Sensing Based on a Novel Mach-Zehnder Interferometer
A novel fiber inline Mach-Zehnder interferometer (MZI) is proposed for simultaneous measurement of curvature and temperature. The sensor composes of single mode-multimode-dispersion compensation-multimode-single mode fiber (MMF-DCF-MMF) structure, using ...
Xiaoyan Sun +4 more
doaj +1 more source
To date, planar waveguides are under development for augmented reality systems with waveguide combiners. The next step of their development is the transition to curved waveguides, which could make the combiners more ergonomic.
Gavril N. Vostrikov +6 more
doaj +1 more source
2010, 1st quarter-; Description based on: 1st quarter 2010; title from PDF caption (viewed on Dec. 7, 2010).; At head of title: Ohio Deferred Compensation.; "A publication of the Ohio Deferred Compensation Board."; Harvested from the web on 12/9 ...
core +4 more sources
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
A Novel Catheter Shape-Sensing Method Based on Deep Learning with a Multi-Core Optical Fiber
In this paper, we propose a novel shape-sensing method based on deep learning with a multi-core optical fiber for the accurate shape-sensing of catheters and guidewires.
Fei Han +3 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The eddy current displacement sensor (ECDS) is used to realize the precise detection of the rotor radial position in the magnetic suspension motor. The eccentricity between the probe axis and the measured surface normal reduces the measurement accuracy ...
Hao Zhan +3 more
doaj +1 more source

