Results 31 to 40 of about 629,535 (260)

A High-Precision Curvature Compensation Reference Circuit for a Cable Accessory Image Acquisition Device

Energies
High-voltage cables are widely used in power transmission and distribution systems, and their accessories (such as connectors, terminals, and insulators) are key parts to ensure the safe and reliable operation of power systems.
Ning Xiao, Yuewei Tian, Xiaosong Peng, Weijun Wang, Wenqiang Zou, Chao Yuan, Qian Zhou   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Low Complexity Compensation for Range-Angle Migration in High-Resolution MIMO Radar Systems

IEEE Access
High angular resolution is essential for fine images in modern radar applications, which typically requires a large virtual antenna array. However, such large arrays give rise to near-field effects, necessitating wavefront-curvature compensation and ...
Gunhwi Moon, Jeong-Hoon Park, Soram Kim, Ohgeun Jee, Jihye Kim, Seong-Cheol Kim   +5 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Other title: Four fifty-seven focus; Other title: Ohio Deferred Compensation 457 focus; Other title: Ohio Deferred Compensation four fifty-seven focus; Other title: Title from "Program newsletters" screen: Participant Focus newsletter

, 2010
2010, 1st quarter-; At head of title: Ohio Deferred Compensation.; "A publication of the Ohio Deferred Compensation Board.

core   +4 more sources

Method for Compensating Aberrations of a Virtual Image Formed by an Augmented Reality Display Based on a Cylindrical Diffractive Waveguide

Applied Sciences, 2023
To date, planar waveguides are under development for augmented reality systems with waveguide combiners. The next step of their development is the transition to curved waveguides, which could make the combiners more ergonomic.
Gavril N. Vostrikov, Nikolay V. Muravyev, Aleksandr E. Angervaks, Roman A. Okun, Anastasia S. Perevoznikova, Jaeyeol Ryu, Andrei N. Putilin   +6 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Simultaneous Curvature and Temperature Sensing Based on a Novel Mach-Zehnder Interferometer

Photonic Sensors, 2019
A novel fiber inline Mach-Zehnder interferometer (MZI) is proposed for simultaneous measurement of curvature and temperature. The sensor composes of single mode-multimode-dispersion compensation-multimode-single mode fiber (MMF-DCF-MMF) structure, using ...
Xiaoyan Sun, Haifeng Du, Xinran Dong, Youwang Hu, Ji’an Duan   +4 more
doaj   +1 more source