Results 61 to 70 of about 12,049 (277)

The Cause of Cushing's Disease

Journal of Neuroendocrinology, 2000
Cushing's disease is one of the most fascinating disorders in the whole of endocrinology, in which a minute tumour in the pituitary gives rise to a whole panoply of symptoms, signs and changes in mood and behaviour. Recent research has begun to identify the molecular changes in these tumours underlying the reduced sensitivity of the tumour cells to ...
openaire   +4 more sources

The potential role of environmentally associated DNA methylation in childhood acute lymphoblastic leukaemia subtypes

International Journal of Cancer, EarlyView.
What's New? The rarity of acute lymphoblastic leukaemia and lack of available environmental data have made the role of environmental factors in genetic subtypes challenging to investigate. Here, the authors performed a CpG‐level analysis to investigate DNA methylation as an intermediate mechanism between environmental risk exposures and acute ...
Jessica R. Saville, Lisa J. Russell, Kay Padget, Akram Ghantous, Jessica Nordlund, Jill A. McKay   +5 more
wiley   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Gut microbial‐derived 3,4‐dihydroxyphenylacetic acid ameliorates reproductive phenotype of polycystic ovary syndrome

iMeta, EarlyView.
By integrating multi‐level and multi‐omics analyses, we identify 3,4‐dihydroxyphenylacetic acid (DHPAA), a gut microbiota‐derived degradation product of dietary flavonoids, as a key bioactive end‐product responsible for the beneficial effects against polycystic ovary syndrome (PCOS).
Pan Li, Li Xie, Huimin Zheng, Yinglin Feng, Feihong Mai, Wenli Tang, Jiajia Wang, Zixin Lan, Shuaijun Lv, Thisun Jayawardana, Sabrina Koentgen, Shuangbin Xu, Zhengwei Wan, Yunjie Chen, Haiyan Xu, Sj Shen, Fan Zhang, Yuanhao Yang, Georgina Hold, Fangjie He, Emad M. El‐Omar, Guangchuang Yu, Xia Chen   +22 more
wiley   +1 more source

Rectal budesonide: A potential game changer after Kasai hepatoportoenterostomy

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Intravenous or oral steroid administration in patients with biliary atresia (BA) after Kasai hepatoportoenterostomy (HPE) is commonly practiced, however, the benefits remain controversial. Some studies suggest no positive effects while risking steroid associated side effects.
Stefanie Langreen, Nathalie Pauer, Eva D. Pfister, Norman Junge, Ulrich Baumann, Omid Madadi‐Sanjani, Claus Petersen, Jens Dingemann, Nagoud Schukfeh   +8 more
wiley   +1 more source

Results of surgical therapy of functioning pituitary adenomas

Biomedical Papers
Introduction. Functioning pituitary adenomas lead to substantial morbidity and increased mortality associated with typical endocrine syndromes. Surgical therapy is an integral part of the management of these tumours. The aim of this study was to evaluate
Vlastimil Novak, Lumir Hrabalek, Jan Schovanek, Zdenek Frysak, Racheal Temitope Ijisesan Perryova, Daniel Pohlodek   +5 more
doaj   +1 more source

Carney complex (CNC)

Orphanet Journal of Rare Diseases, 2006
The Carney complex (CNC) is a dominantly inherited syndrome characterized by spotty skin pigmentation, endocrine overactivity and myxomas. Skin pigmentation anomalies include lentigines and blue naevi.
Bertherat Jérôme
doaj   +1 more source

Folate‐Associated DNA Methylation and Chemotherapy‐Induced Toxicities in Patients With Colorectal Cancer

Molecular Nutrition &Food Research, EarlyView.
Over half of patients with colorectal cancer experience severe chemotherapy‐induced side effects. The B‐vitamin folate may play a role in these side effects, potentially by altering DNA methylation, a mechanism of gene regulation. Our comprehensive literature search identified studies investigating DNA methylation associated with folate status/intake ...
Nienke R. K. Zwart, Dieuwertje E. Kok, Sajini N. H. Ariyaratne, Jill A. McKay   +3 more
wiley   +1 more source

Endothelial progenitor cells in a patient with Cushing's syndrome before and after adrenal surgery

Journal of Clinical and Translational Endocrinology Case Reports, 2018
Endothelial progenitor cells (EPCs) exert a pivotal role in vascular repairing and vascular function. Low EPCs levels have been detected in patients with endocrine disease at increased cardiovascular risk such as diabetes, hypothyroidism, and ...
Roberto Negro
doaj  

Strong gradients, cool performance: A 64‐channel array coil with concurrent field monitoring and thermal control for ex vivo diffusion‐weighted brain imaging using the 3T connectome 2.0 MRI scanner

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose High‐resolution ex vivo diffusion‐weighted imaging (dMRI) with high b$$ b $$‐values presents significant challenges, including low signal‐to‐noise ratio (SNR), magnetic field perturbations, and temperature‐related measurement shifts.
Alina Müller, Mirsad Mahmutovic, Mona Alem, Gabriel Ramos‐Llordén, Dongsuk Sung, Manisha Shrestha, Sam‐Luca J.D. Hansen, Chaimaa Chemlali, Anpreet Ghotra, Jason Stockmann, Choukri Mekkaoui, Lawrence L. Wald, Anastasia Yendiki, Susie Y. Huang, Boris Keil   +14 more
wiley   +1 more source