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Diagnóstico laboratorial de síndrome de Cushing.
Cushing's syndrome is a diagnostic challenging endocrinous entity. Many laboratorial examinations are available for the study of these patients. Available examinations are not absolutely trustworthy for its diagnosis, so that, very often, it is necessary
Marta Alves+2 more
doaj +1 more source
Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice. [PDF]
Carney complex (CNC) is an inherited neoplasia syndrome with endocrine overactivity. Its most frequent endocrine manifestation is primary pigmented nodular adrenocortical disease (PPNAD), a bilateral adrenocortical hyperplasia causing pituitary ...
Isabelle Sahut-Barnola+14 more
doaj +1 more source
Cushing's syndrome is associated with increased mortality, mainly due to cardiovascular complications, which are sustained by the common development of systemic arterial hypertension and metabolic syndrome, which partially persist after the disease ...
A. Isidori+7 more
semanticscholar +1 more source
Abstract Using intersectionality as a critical theoretical framework and analytical tool, this study investigated the HIV/AIDS information practices of Black sexual minority men (SMM). Twenty‐two Black SMM were interviewed about their HIV/AIDS‐related information practices.
Megan Threats
wiley +1 more source
Cushing’s syndrome: epidemiology and developments in disease management
Cushing’s syndrome is a rare disorder resulting from prolonged exposure to excess glucocorticoids. Early diagnosis and treatment of Cushing’s syndrome is associated with a decrease in morbidity and mortality. Clinical presentation can be highly variable,
Susmeeta T. Sharma+2 more
semanticscholar +1 more source
Epidemiology of Cushing’s Syndrome [PDF]
Overt Cushing’s syndrome is a rare disorder with an annual incidence of 2–3/million of which benign adrenal adenomas account for 0.6/million. The female:male ratio is 3:1. Preliminary data indicate a high proportion of subclinical Cushing’s syndrome in certain risk populations such as patients with type 2 diabetes or osteoporosis.
Steffensen, Charlotte+3 more
openaire +4 more sources
Clonal Composition of Human Adrenocortical Neoplasms [PDF]
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Abdelhamid, S.+7 more
core
Abstract Aims Prednisone is a widely used glucocorticoid in the treatment of lupus, although its dosing is often determined empirically. Prednisolone, the active metabolite of prednisone, is found in its free form in the serum. The goal of this study was to develop a population pharmacokinetic model in patients with systemic lupus erythematosus (SLE ...
Naïm Bouazza+26 more
wiley +1 more source
Luteinizing hormone (LH)-responsive Cushing's syndrome: the demonstration of LH receptor messenger ribonucleic acid in hyperplastic adrenal cells, which respond to chorionic gonadotropin and serotonin agonists in vitro [PDF]
In a substantial part of adrenal adenomas and hyperplasias from patients with Cushing's syndrome, cortisol production is controlled by the expression of aberrant hormone receptors on adrenocortical cells.
Bonjer, H.J. (Jaap)+10 more
core +7 more sources
Iatrogenic cushing's syndrome in children following nasal steroid
Cushing syndrome is a hormonal disorder caused by prolonged exposure of body tissue to cortisol. We report two cases of iatrogenic Cushing's syndrome in two Nigerian children following intranasal administration of aristobed-N (Betamethasone+Neomycin ...
Isaac Oludare Oluwayemi+7 more
doaj +1 more source