Results 51 to 60 of about 206,810 (287)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Optimal Software Versioning Strategy Considering Customization and Consumer Deliberation Behavior
Journal of Theoretical and Applied Electronic Commerce Research, 2023 This study investigates the optimal versioning problem when a monopoly software provider bears the deliberation cost to help reduce consumer uncertainty about SaaS customization.
Wenjun Shu +3 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Assessing Operability on Berthed Ships. Common Approaches, Present and Future Lines
Journal of Marine Science and Engineering, 2020 The revenue of a ship company, a terminal, a port and even the whole logistic chain largely depends on the performance of (un)loading operations inside port areas. However, they are conditioned by met-ocean agents that exert stresses on fixed structures,
Rafael Molina-Sanchez +7 more
doaj +1 more source
DIVIS: Integrated and Customizable Pipeline for Cancer Genome Sequencing Analysis and Interpretation
Frontiers in Oncology, 2021 Next-generation sequencing (NGS) has drastically enhanced human cancer research, but diverse sequencing strategies, complicated open-source software, and the identification of massive numbers of mutations have limited the clinical application of NGS ...
Xiaoyu He +13 more
doaj +1 more source
Extending the institutional repository to include undergraduate research [PDF]
, 2016 While a primary strategy of scholarly communication initiatives has been to encourage faculty participation in institutional repositories (IRs), with some process and workflow customization, IR participation can be successfully extended to undergraduate ...
Exline, Eleta
core +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Postgraduate Medical Journal, 1973 Summary It seems fundamentally improbable that different mental symptoms and personality disorders should be relieved by one single form of operation on the brain. The present paper describes five operations which can be performed with benefit to different types of psychiatric abnormality; namely, unilateral temporal lobectomy ...
openaire +2 more sources
Customer‐Based Customization and Price Competition*
The Journal of Industrial Economics, 2022 Among the many consequences for production processes, new technologies, including 3D‐printing and web‐based co‐design, provide end‐users with increasingly effective means to locally reshape and co‐produce products to fit their needs, decentralizing part of the production process. But do firms have an incentive to design goods that are self‐customizable
Stefano Colombo, Paolo Garella
openaire +3 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source