Recalcitrant Cutaneous Mastocytosis Treated With Genetically Informed Targeted Therapy: A Case Report [PDF]
International Journal of Dermatology and Venerology, 2023 Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease.
Laura Gleason +7 more
doaj +2 more sources
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2020 Review on cutaneous mastocytosis, with data on clinics, pathology, and involved genes.
Karen M. Chisholm
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When Mast Cells Run Amok: A Comprehensive Review and Case Study on Severe Neonatal Diffuse Cutaneous Mastocytosis. [PDF]
Genes (Basel), 2023 Neonatal diffuse cutaneous mastocytosis (NDCM) is defined as the infiltration of the epidermis by a clonal proliferation of mast cells, observed at birth, without initial signs of systemic involvement. The typical driver mutation is in the KIT gene.
Olteanu EG +3 more
europepmc +2 more sources
A case report of primary cutaneous marginal zone B-cell lymphoma with mastocytosis [PDF]
SAGE Open Medical Case Reports, 2021 A 53-year-old man presented with asymptomatic, dusky reddish nodules on his trunk, which had persisted for 7 years. Histological findings showed nodular to diffuse dermal infiltration of lymphocytes with irregular nuclei, eosinophils, plasma cells, and ...
Hyun Yi Lee, Joong Sun Lee, Dae Won Koo
doaj +2 more sources
Cutaneous mastocytosis: diagnostic challenges and dietary influences. [PDF]
Dermatol ReportsCutaneous mastocytosis (CM) is a rare condition characterized by abnormal mast cell proliferation in the skin. We present the case of a 65-year-old man with recurrent urticaria-like rashes persisting for more than eight years.
Al-Soufi L +3 more
europepmc +2 more sources
Dermoscopic Features of Different Forms of Cutaneous Mastocytosis: A Systematic Review. [PDF]
J Clin Med, 2022 The term mastocytosis refers to a heterogeneous group of disorders characterised by accumulation of clonal mast cells in different organs, most commonly in the skin. Little is known about the role of dermoscopy in the diagnostics of mastocytosis. To date,
Sławińska M +5 more
europepmc +2 more sources
Cutaneous Mastocytosis in Childhood-Update from the Literature. [PDF]
J Clin Med, 2021 Mastocytosis (M) represents a systemic pathology characterized by increased accumulation and clonal proliferation of mast cells in the skin and/or different organs.
Sandru F +6 more
europepmc +2 more sources
Diffuse Cutaneous Mastocytosis: A Current Understanding of a Rare Disease. [PDF]
Int J Mol SciMastocytosis is a heterogeneous disease characterized by the expansion and accumulation of neoplastic mast cells in various tissues. Diffuse cutaneous mastocytosis (DCM) is a rare and most severe form of cutaneous mastocytosis, which typically occurs in ...
Rydz A +6 more
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Histopathological characteristics are instrumental to distinguish monomorphic from polymorphic maculopapular cutaneous mastocytosis in children. [PDF]
Clin Exp Dermatol, 2022 Mastocytosis is characterized by the accumulation of mast cells (MCs) in the skin or other organs, and can manifest at any age. A significant number of paediatric mastocytosis cases persist after puberty.
Hermans MAW +8 more
europepmc +2 more sources
Bullous Mastocytosis: A Rare Variant of Diffuse Cutaneous Mastocytosis. [PDF]
CureusMastocytosis is a disease of the mast cells caused by an increase in the number of mast cells due to abnormal proliferation. The disease is associated with a mutation in the c-kit gene, which is a key factor in the development of mast cells. Mastocytosis
Almheiri SK +3 more
europepmc +2 more sources