Results 1 to 10 of about 134,108 (165)

Primary dermal melanoma: a rare subtype of cutaneous melanoma [PDF]

open access: yesMelanoma Management
Primary dermal melanoma (PDM) is a rare subtype of cutaneous melanoma, with involvement of the dermis/subcutaneous tissue or both, but no involvement of the epidermis.
Erol Benlier   +2 more
doaj   +2 more sources

Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis

open access: yesiScience, 2023
Summary: AMP-activated protein kinase (AMPK) is a critical cellular energy sensor at the interface of metabolism and cancer. However, the role of AMPK in carcinogenesis remains unclear.
Ping Yuan   +9 more
doaj   +1 more source

Differences and Similarities in Epidemiology and Risk Factors for Cutaneous and Uveal Melanoma

open access: yesMedicina, 2023
Both cutaneous melanoma (CM) and uveal melanoma (UM) represent important causes of morbidity and mortality. In this review, we evaluate the available knowledge on the differences and similarities between cutaneous melanoma and uveal melanoma, focusing on
Daciana Elena Brănișteanu   +10 more
doaj   +1 more source

Epidemiological and histopathological aspects of primary cutaneous melanoma in residents of Joinville, 2003-2014 [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Background: The worldwide incidence of cutaneous melanoma (CM) has been continuously increasing over the last decades. Primary and secondary prevention, with attention to risk factors and early diagnosis, remain the cornerstone for reducing the burden
Raquel Bissacotti Steglich   +5 more
doaj   +1 more source

Melanoma inhibitory activity in Brazilian patients with cutaneous melanoma [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
BACKGROUND: Melanoma inhibitory activity is a protein secreted by melanoma cells and has been used as a tumor marker. Increased Melanoma inhibitory activity serum levels are related to metastatic disease or tumor recurrence.
Macanori Odashiro   +6 more
doaj   +2 more sources

Differences in the diagnosis of primary cutaneous melanoma in the public and private healthcare systems in Joinville, Santa Catarina State, Brazil [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Background: Cutaneous melanoma accounts for up to 80% of deaths caused by skin cancer. Diagnostic suspicion and access to medical care and early intervention in suspected cases is vital to the patient’s prognosis.
Raquel Bissacotti Steglich   +5 more
doaj   +2 more sources

PGAM5: A necroptosis gene associated with poor tumor prognosis that promotes cutaneous melanoma progression

open access: yesFrontiers in Oncology, 2022
Cutaneous melanoma is the deadliest type of skin cancer, and its highly aggressive and metastatic nature leads to an extremely poor prognosis. Necrotizing apoptosis, a specific form of programmed cell death, has been extensively studied in recent years ...
Jianzhong Peng   +5 more
doaj   +1 more source

Combining single-cell and transcriptomic analysis revealed the immunomodulatory effect of GOT2 on a glutamine-dependent manner in cutaneous melanoma

open access: yesFrontiers in Pharmacology, 2023
Background: Reprogramming in glutamine metabolism is a hallmark of cancers, while its role in cutaneous melanoma has not been studied at great length.Methods: Here, we constructed a glutamine metabolism-related prognostic signature in cutaneous melanoma ...
Lebin Song, Xiyi Wei, Xi Zhang, Yan Lu
doaj   +1 more source

Clinical features, molecular pathology, and immune microenvironmental characteristics of acral melanoma

open access: yesJournal of Translational Medicine, 2022
Acral melanoma (AM) has unique biology as an aggressive subtype of melanoma. It is a common subtype of melanoma in races with darker skin tones usually diagnosed at a later stage, thereby presenting a worse prognosis compared to cutaneous melanoma.
Jianping Gui, Zhen Guo, Di Wu
doaj   +1 more source

Knockdown of FOXRED2 restrains proliferation, invasion and migration of human melanoma cells

open access: yesHeliyon, 2023
Objectives: This experiment investigated the role of the FAD-dependent oxidoreductase domain-containing 2 (FOXRED2) in the development of cutaneous malignant melanoma.
Mujin Li   +10 more
doaj   +1 more source

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