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Primary dermal melanoma: a rare subtype of cutaneous melanoma [PDF]

open access: yesMelanoma Management
Primary dermal melanoma (PDM) is a rare subtype of cutaneous melanoma, with involvement of the dermis/subcutaneous tissue or both, but no involvement of the epidermis.
Erol Benlier   +2 more
doaj   +3 more sources

Cutaneous melanoma

open access: yesNature Reviews Disease Primers
Cutaneous melanoma is a common cancer in Australia and New Zealand, Europe, and North America, and its incidence is still increasing in many regions. Ultraviolet (UV) radiation exposure (for example, through excessive sunlight exposure) remains the primary risk factor for melanoma; however, public awareness campaigns have led to a marked reduction in ...
Alpaslan Tasdogan   +2 more
exaly   +9 more sources

Omics in Cutaneous Melanoma. [PDF]

open access: yesAsian Pac J Cancer Prev
The advancement of multidimensional omics technologies holds immense promise for the future of medical treatment, particularly in addressing a wide range of human illnesses. Melanoma, which ranks among the most aggressive malignant pathologies affecting the skin, is a complex and heterogeneous oncological condition.
Spirina LV   +6 more
europepmc   +3 more sources

Loss of AMPKα2 promotes melanoma tumor growth and brain metastasis

open access: yesiScience, 2023
Summary: AMP-activated protein kinase (AMPK) is a critical cellular energy sensor at the interface of metabolism and cancer. However, the role of AMPK in carcinogenesis remains unclear.
Ping Yuan   +9 more
doaj   +1 more source

Differences and Similarities in Epidemiology and Risk Factors for Cutaneous and Uveal Melanoma

open access: yesMedicina, 2023
Both cutaneous melanoma (CM) and uveal melanoma (UM) represent important causes of morbidity and mortality. In this review, we evaluate the available knowledge on the differences and similarities between cutaneous melanoma and uveal melanoma, focusing on
Daciana Elena Brănișteanu   +10 more
doaj   +1 more source

Epidemiological and histopathological aspects of primary cutaneous melanoma in residents of Joinville, 2003-2014 [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Background: The worldwide incidence of cutaneous melanoma (CM) has been continuously increasing over the last decades. Primary and secondary prevention, with attention to risk factors and early diagnosis, remain the cornerstone for reducing the burden
Raquel Bissacotti Steglich   +5 more
doaj   +1 more source

Melanoma inhibitory activity in Brazilian patients with cutaneous melanoma [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2015
BACKGROUND: Melanoma inhibitory activity is a protein secreted by melanoma cells and has been used as a tumor marker. Increased Melanoma inhibitory activity serum levels are related to metastatic disease or tumor recurrence.
Macanori Odashiro   +6 more
doaj   +2 more sources

Differences in the diagnosis of primary cutaneous melanoma in the public and private healthcare systems in Joinville, Santa Catarina State, Brazil [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Background: Cutaneous melanoma accounts for up to 80% of deaths caused by skin cancer. Diagnostic suspicion and access to medical care and early intervention in suspected cases is vital to the patient’s prognosis.
Raquel Bissacotti Steglich   +5 more
doaj   +2 more sources

PGAM5: A necroptosis gene associated with poor tumor prognosis that promotes cutaneous melanoma progression

open access: yesFrontiers in Oncology, 2022
Cutaneous melanoma is the deadliest type of skin cancer, and its highly aggressive and metastatic nature leads to an extremely poor prognosis. Necrotizing apoptosis, a specific form of programmed cell death, has been extensively studied in recent years ...
Jianzhong Peng   +5 more
doaj   +1 more source

Clinical features, molecular pathology, and immune microenvironmental characteristics of acral melanoma

open access: yesJournal of Translational Medicine, 2022
Acral melanoma (AM) has unique biology as an aggressive subtype of melanoma. It is a common subtype of melanoma in races with darker skin tones usually diagnosed at a later stage, thereby presenting a worse prognosis compared to cutaneous melanoma.
Jianping Gui, Zhen Guo, Di Wu
doaj   +1 more source

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