Long non-coding RNAs in cutaneous melanoma : clinical perspectives [PDF]
, 2017 Metastatic melanoma of the skin has a high mortality despite the recent introduction of targeted therapy and immunotherapy. Long non-coding RNAs (lncRNAs) are defined as transcripts of more than 200 nucleotides in length that lack protein-coding ...
Brochez, Lieve +4 more
core +1 more source
Human plasmacytoid dendritic cells and cutaneous melanoma [PDF]
, 2020 The prognosis of metastatic melanoma (MM) patients has remained poor for a long time. However, the recent introduction of effective target therapies (BRAF and MEK inhibitors for BRAFV600-mutated MM) and immunotherapies (anti-CTLA-4 and anti-PD-1) has ...
Bugatti, Mattia +4 more
core +2 more sources
Human Pathology: Case Reports, 2020 To explore the expression and clinical significance of major related genes in cutaneous melanoma based on the Cancer Genome Atlas (TCGA) datasets. Five genes with high mutation rate in cutaneous melanoma were screened.
Cui-hua Ren, Ying Ruan
doaj +1 more source
A Non-cutaneous Form of Melanoma in a Goat during Meat Inspection: a Case Report [PDF]
Archives of Razi Institute, 2021 Malignant melanoma is a neoplasm that originates from melanocytes. This tumor is observed in cutaneous and non-cutaneous forms, and it is considered one of the most life-threatening types of cancers.
A Hatefi +3 more
doaj +1 more source
BRAFV600E mutation positive metastatic melanoma in a young woman treated with anti-BRAF/anti MEK combination: a case report [PDF]
, 2015 The recent Combi-v [1] and Combi-d [2,3], phase III randomized trials, showed, respectively, an OS benefit with Dabrafenib/Trametinib combination versus Vemurafenib and an improvement in PFS and ORR with the same combination versus Dabrafenib alone ...
CORTESI, Enrico +6 more
core +2 more sources
Lymphatic drainage patterns of head and neck cutaneous melanoma: does primary melanoma site correlate with anatomic distribution of pathologically involved lymph nodes? [PDF]
, 2012 The aim of this study was to analyse patterns of metastatic spread from cutaneous head and neck melanoma, which are said to be highly variable.
Lukšić, Ivica +3 more
core +1 more source
Alcohol drinking, smoking, and cutaneous melanoma risk: Mendelian randomization analysis
Gaceta Sanitaria, 2023 Objective: To investigate the causal relationship between poor lifestyle habits, such as smoking and drinking, and cutaneous malignant melanoma. Method: In the present study, alcohol consumption and smoking were used as exposure factors, and single ...
Jiaxiang Xu +4 more
doaj +1 more source
Total skin self-examination at home for people treated for cutaneous melanoma : development and pilot of a digital intervention [PDF]
, 2015 This work was funded by the RCUK Digital Economy award to the dot.rural Digital Economy Hub, University of Aberdeen; award reference: EP/G066051/1. The Experience Laboratory event was supported in part by a separate award from the University of Aberdeen ...
Allan, Julia L +7 more
core +3 more sources
ERBB1/2/3 Expression, Prognosis, and Immune Infiltration in Cutaneous Melanoma
Frontiers in Genetics, 2021 BackgroundThe four ERBB tyrosine kinase family members [ERBB1 (epidermal growth factor receptor, EGFR), ERBB2 (HER2), ERBB3 (HER3), and ERBB4 (HER4)] (ERBB receptor family) have been shown, according to previous studies, to be related to the cutaneous ...
Shougang Liu +5 more
doaj +1 more source
Metastases risk in thin cutaneous melanoma: Prognostic value of clinical-pathologic characteristics and mutation profile [PDF]
, 2018 Background: A high percentage of patients with thin melanoma (TM), defined as lesions with Breslow thickness ≤1 mm, presents excellent long-term survival, however, some patients develop metastases.
Calvieri, Stefano +12 more
core +1 more source