Results 41 to 50 of about 369,066 (292)

Primary cilium depletion typifies cutaneous melanoma in situ and malignant melanoma. [PDF]

PLoS ONE, 2011
Cutaneous melanoma is a lethal malignancy that arises spontaneously or via in situ precursor neoplasms. While melanoma in situ and locally invasive malignant melanoma can be cured surgically, these lesions can sometimes be difficult to distinguish from ...
Jinah Kim, Salma Dabiri, E Scott Seeley
doaj   +1 more source

Genetics of Cutaneous Melanoma

Journal of Investigative Dermatology, 1994
A portion of melanoma is familial and has been associated with atypical mole syndrome. This review outlines the current understanding of the genetics of melanoma and the relationship to cutaneous nevus phenotypes. A review of genetic studies of melanoma is presented, including linkage studies. Data from a linkage study of 12 Utah kindreds and one Texas
Meyer, Laurence J, Zone, John H
openaire   +2 more sources

Functional Prediction of Long Noncoding RNAs in Cutaneous Melanoma Using a Systems Biology Approach

Bioinformatics and Biology Insights, 2021
Cutaneous melanoma is the most aggressive type of skin cancer which its incidence has significantly increased in recent years worldwide. Thus, more investigations are required to identify the underlying mechanisms of melanoma malignant transformation and
Mozhdeh Shahmoradi, Zahra Rezvani
doaj   +1 more source

Cutaneous malignant melanoma in skin of color individuals

Nigerian Journal of Medicine, 2021
Cutaneous malignant melanoma (CMM) is a malignancy with a worldwide incidence. Literature is replete in the Caucasian population, but in skin of color, there is a dearth of literature. Documented reports of the epidemiology of cutaneous melanoma reveal a
Ehiaghe Lonia Anaba
doaj   +1 more source

Omics in Cutaneous Melanoma. [PDF]

Asian Pac J Cancer Prev
The advancement of multidimensional omics technologies holds immense promise for the future of medical treatment, particularly in addressing a wide range of human illnesses. Melanoma, which ranks among the most aggressive malignant pathologies affecting the skin, is a complex and heterogeneous oncological condition.
Spirina LV, Bogdanova VA, Chizhevskaya SY, Stepovaya EA, Nosareva OL, Zinnurova AB, Barkysheva AA.   +6 more
europepmc   +3 more sources

Implications of tumor-positive sentinel lymph nodes in single vs multiple nodal basins in melanoma

Frontiers in Oncology
BackgroundMelanoma patients’ prognosis is based on the primary tumor characteristics and the tumor status of the regional lymph nodes. The advent of lymphoscintigraphy with SLN biopsy (SLNB) has shown that melanoma can drain to multiple nodal basins but ...
Emiliano Reyes, Kristel Lourdault, Judi Anne Ramiscal, Stacey Stern, Richard Essner, Richard Essner   +5 more
doaj   +1 more source

Variation in the Surgical Care of Early Stage Melanoma Based on Surgical Subspecialty: Evaluation of Large Healthcare System

Annals of Surgery Open
Objective:. To investigate how different surgeons’ subspecialties comply with treatment guidelines for early stage melanoma. Background:. The National Comprehensive Cancer Network developed evidence-based guidelines for surgical margins, depth of ...
Kristel Lourdault, PhD, DVM, Arthur W. Cowman, BS, Emiliano Reyes, MS, Danny Lascano, MD, Udai S. Sibia, MD, MBA, Brett Crosby, BS, Tyler Aguilar, BS, Deanna Rider, Stacey Stern, MS, Richard Essner, MD, FACS   +9 more
doaj   +1 more source

Selective induction of cell death in melanoma cell lines through targeting of Mcl-1 and A1. [PDF]

, 2012
Melanoma is an often fatal form of skin cancer which is remarkably resistant against radio- and chemotherapy. Even new strategies that target RAS/RAF signaling and display unprecedented efficacy are characterized by resistance mechanisms.
Berking, Carola, Senft Daniela, Robert Besch, Carola Berking, Saskia A Graf, Claudia Kammerbauer, Thomas Ruzicka, Graf, Saskia A., Besch, Robert, Graf Saskia A., Senft, Daniela, Berking Carola, Kammerbauer, Claudia, Daniela Senft, Besch Robert, Kammerbauer Claudia, Ruzicka, Thomas, Saskia A. Graf, Ruzicka Thomas   +18 more
core   +2 more sources

Prospects for non-immunological molecular therapeutics in melanoma [PDF]

, 2010
In 2006 there were 60,000 new cases of cutaneous melanoma in the European Union and 13,000 deaths (www.europeancancerleagues.org). Currently available systemic treatment options for metastatic melanoma, including both cytotoxic and immunologic therapies,
Tryfonopoulos, Dimitrios, Eustace, Alexander J., Mahgoub, Thamir, O\u27Donovan, Norma, Crown, John, O'Donovan, Norma   +5 more
core   +2 more sources

Serum Level of Soluble CD163 May Be a Predictive Marker of the Effectiveness of Nivolumab in Patients With Advanced Cutaneous Melanoma

Frontiers in Oncology, 2018
Antibodies against programmed cell death protein 1, such as nivolumab and pembrolizumab, are widely used for treating various cancers, including advanced melanoma.
Taku Fujimura, Yota Sato, Kayo Tanita, Yumi Kambayashi, Atsushi Otsuka, Yasuhiro Fujisawa, Koji Yoshino, Shigeto Matsushita, Takeru Funakoshi, Hiroo Hata, Yuki Yamamoto, Hiroshi Uchi, Yumi Nonomura, Ryota Tanaka, Megumi Aoki, Keisuke Imafuku, Hisako Okuhira, Naoko Wada, Hiroyuki Irie, Takanori Hidaka, Akira Hashimoto, Setsuya Aiba   +21 more
doaj   +1 more source