Results 41 to 50 of about 134,257 (306)

Genetic variants in ELOVL2 and HSD17B12 predict melanoma‐specific survival [PDF]

, 2019
Fatty acids play a key role in cellular bioenergetics, membrane biosynthesis and intracellular signaling processes and thus may be involved in cancer development and progression.
Amos, Christopher I., Dai, Wei, Fang, Shenying, Jie, Ge, Lee, Jeffrey E., Li, Chunying, Li, Xin, Liu, Hongliang, Luo, Sheng, Nan, Hongmei, Wei, Qingyi, Xu, Xinyuan, Zhu, Dakai   +12 more
core   +1 more source

Genetics of Cutaneous Melanoma

Journal of Investigative Dermatology, 1994
A portion of melanoma is familial and has been associated with atypical mole syndrome. This review outlines the current understanding of the genetics of melanoma and the relationship to cutaneous nevus phenotypes. A review of genetic studies of melanoma is presented, including linkage studies. Data from a linkage study of 12 Utah kindreds and one Texas
Meyer, Laurence J, Zone, John H
openaire   +2 more sources

Implications of tumor-positive sentinel lymph nodes in single vs multiple nodal basins in melanoma

Frontiers in Oncology
BackgroundMelanoma patients’ prognosis is based on the primary tumor characteristics and the tumor status of the regional lymph nodes. The advent of lymphoscintigraphy with SLN biopsy (SLNB) has shown that melanoma can drain to multiple nodal basins but ...
Emiliano Reyes, Kristel Lourdault, Judi Anne Ramiscal, Stacey Stern, Richard Essner, Richard Essner   +5 more
doaj   +1 more source

Biology of advanced uveal melanoma and next steps for clinical therapeutics [PDF]

, 2014
Uveal melanoma is the most common intraocular malignancy although it is a rare subset of all melanomas. Uveal melanoma has distinct biology relative to cutaneous melanoma, with widely divergent patient outcomes.
Bastian, BC, Bowcock, AM, Carvajal, RD, Flaherty, KT, Gershenwald, JE, Gutkind, JS, Luke, JJ, McKenna, KC, Patel, PM, Sato, T, Selig, S, Sossman, JA, Streicher, HZ, Sznol, M, Thurin, M, Triozzi, PL, Van Meir, EG, Welch, J   +17 more
core   +1 more source

Variation in the Surgical Care of Early Stage Melanoma Based on Surgical Subspecialty: Evaluation of Large Healthcare System

Annals of Surgery Open
Objective:. To investigate how different surgeons’ subspecialties comply with treatment guidelines for early stage melanoma. Background:. The National Comprehensive Cancer Network developed evidence-based guidelines for surgical margins, depth of ...
Kristel Lourdault, PhD, DVM, Arthur W. Cowman, BS, Emiliano Reyes, MS, Danny Lascano, MD, Udai S. Sibia, MD, MBA, Brett Crosby, BS, Tyler Aguilar, BS, Deanna Rider, Stacey Stern, MS, Richard Essner, MD, FACS   +9 more
doaj   +1 more source

Non melanoma skin cancer pathogenesis overview [PDF]

, 2018
(1)Background: Non-melanoma skin cancer is the most frequently diagnosed cancer in humans. The process of skin carcinogenesis is still not fully understood.
Bottoni Ugo, Cantisani Carmen, Didona Dario, Paolino Giovanni   +3 more
core   +1 more source

Exponentially Increasing Incidences of Cutaneous Malignant Melanoma in Europe Correlate with Low Personal Annual UV Doses and Suggests 2 Major Risk Factors [PDF]

, 2015
For several decades the incidence of cutaneous malignant melanoma (CMM) steadily increased in fair-skinned, indoor-working people around the world. Scientists think poor tanning ability resulting in sunburns initiate CMM, but they do not understand why ...
Akslen LA, Beer TM, Chida K, Cornwell ML, Devgun MS, Dianne E Godar, Eisman JA, Elwood JM, European Commission, Frampton RJ, Godar DE, Köstner K, Madhan Subramanian, Robinson ES, Samira Ashrafi, Stephen J Merrill, Tewari A   +16 more
core   +2 more sources

Serum Level of Soluble CD163 May Be a Predictive Marker of the Effectiveness of Nivolumab in Patients With Advanced Cutaneous Melanoma

Frontiers in Oncology, 2018
Antibodies against programmed cell death protein 1, such as nivolumab and pembrolizumab, are widely used for treating various cancers, including advanced melanoma.
Taku Fujimura, Yota Sato, Kayo Tanita, Yumi Kambayashi, Atsushi Otsuka, Yasuhiro Fujisawa, Koji Yoshino, Shigeto Matsushita, Takeru Funakoshi, Hiroo Hata, Yuki Yamamoto, Hiroshi Uchi, Yumi Nonomura, Ryota Tanaka, Megumi Aoki, Keisuke Imafuku, Hisako Okuhira, Naoko Wada, Hiroyuki Irie, Takanori Hidaka, Akira Hashimoto, Setsuya Aiba   +21 more
doaj   +1 more source

Anorectal Melanoma [PDF]

, 2018
Anorectal melanoma (AM) is a rare malignancy, characterized by aggressive behavior and a poor prognosis. AM is more frequent in female patients aged over 50 years.
Dario Didona, Giovanni Paolino, Giulia Macrì, Santo Raffaele Mercuri., Stefano Calvieri   +4 more
core   +1 more source

Hierarchical Clustering of Cutaneous Melanoma Based on Immunogenomic Profiling

Frontiers in Oncology, 2020
Cutaneous melanoma is an aggressive malignancy with high heterogeneity. Several studies have been performed to identify cutaneous melanoma subtypes based on genomic profiling.
Jie Yu, Minyue Xie, Shengfang Ge, Peiwei Chai, Yixiong Zhou, Jing Ruan   +5 more
doaj   +1 more source