Results 51 to 60 of about 134,257 (306)

Identification of a five-miRNA signature predicting survival in cutaneous melanoma cancer patients [PDF]

PeerJ, 2019
Background Cutaneous melanoma (CM) is the deadliest form of skin cancer. Numerous studies have revealed that microRNAs (miRNAs) are expressed abnormally in melanoma tissues.
Tao Lu, Shuang Chen, Le Qu, Yunlin Wang, Hong-duo Chen, Chundi He   +5 more
doaj   +2 more sources

Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours [PDF]

, 2016
Natural killer (NK) lymphocytes are part of the innate immune system and are important in immune protection against tumourigenesis. NK cells display a broad repertoire of activating and inhibitory cell surface receptors that regulate NK cell activity ...
Filtjens, Jessica, Keirsse, Jiri, Kerre, Tessa, Leclercq, Georges, Plum, Jean, Taghon, Tom, Taveirne, Sylvie, Van Acker, Aline, Van Ammel, Els, Van Ginderachter, Jo A, Vandekerckhove, Bart   +10 more
core   +2 more sources

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Epidermotropic metastatic melanoma with perilesional depigmentation in an Indian male

Indian Journal of Dermatology, 2013
Melanoma is a rare form of cutaneous malignancy encountered in the dark skin population. Epidermotropic metastatic melanoma is a rare form of cutaneous metastatic melanoma which can mimic primary melanoma on histopathology.
Bhavana Doshi, Sunanda Mahajan, Uday S Khopkar, Vidya Kharkar, Prachi Agarwal   +4 more
doaj   +1 more source

Identification of the m6A RNA Methylation Regulators WTAP as a Novel Prognostic Biomarker and Genomic Alterations in Cutaneous Melanoma

Frontiers in Molecular Biosciences, 2021
Background: The purpose of our research was to establish a gene signature and determine the prognostic value of m6A methylation regulators in cutaneous melanoma and WTAP as a protective gene in cutaneous melanoma prognosis, we also evaluated gene ...
Zi-Yi Feng, Ting Wang, Xin Su, Shu Guo
doaj   +1 more source

Smart Closed‐Loop Systems in Personalized Healthcare: Advances and Outlook

Advanced Materials Technologies, EarlyView.
A smart closed‐loop e‐textile integrates multimodal sensing, onboard processing, wireless communication, and wearable power to enable real‐time physiological/biochemical monitoring and feedback‐controlled therapy. ABSTRACT Smart textiles represent a revolutionary frontier in healthcare, seamlessly blending fabric and advanced technologies to create ...
Safoora Khosravi, Sang Won Lee, Mohammad Abrar Uddin, Sina Hassanpoor, Neha Suvindran, Katherine Le, Harun Arkaz, Harishkumar Narayana, Saeid Soltanian, Danial Khorsandi, Negar Hosseinzadeh Kouchehbaghi, Taeil Kim, Yangzhi Zhu   +12 more
wiley   +1 more source

Clinical Characteristics of Cutaneous Melanoma and Second Primary Malignancies in a Dutch Hospital-Based Cohort of Cutaneous Melanoma Patients

Dermatology Research and Practice, 2009
The increasing number of living cutaneous melanoma patients and the increased risk of developing a second primary tumour incited us to analyse the clinical characteristics of cutaneous melanoma and define the frequency, site, and type of second primary ...
Haike M. J. van der Velden, Michelle M. van Rossum, Willeke A. M. Blokx, Jan B. M. Boezeman, Marie-Jeanne P. Gerritsen   +4 more
doaj   +1 more source

The Impact of Hyaluronan on Tumor Progression in Cutaneous Melanoma

Frontiers in Oncology, 2022
The incidence of cutaneous melanoma is rapidly increasing worldwide. Cutaneous melanoma is an aggressive type of skin cancer, which originates from malignant transformation of pigment producing melanocytes.
Piia Takabe, Hanna Siiskonen, Aino Rönkä, Kirsi Kainulainen, Sanna Pasonen-Seppänen   +4 more
doaj   +1 more source

Melanoma [PDF]

, 2012
Melanoma is a relatively common neoplasm which is increasing in incidence. Melanoma appears as a variegated irregular maculopapular lesion usually on the skin, but possibly on mucosae, conjunctiva, orbit, nails and oesophagus. They may be black, brown,
Magri, Stephanie, Pace, Keith
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source