Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas +3 more
wiley +1 more source
Years of life lost in cutaneous squamous cell carcinoma: analysis of a prospective cohort of 1400 patients. [PDF]
Dietz K, Eigentler TK, Breuninger H.
europepmc +1 more source
Long‐Term Care of OLP Patients: A Retrospective Study From a Single Hospital Outpatient Clinic
ABSTRACT Background Oral lichen planus (OLP) is a chronic immune‐mediated disorder with malignant potential. However, its real‐world clinical course remains incompletely characterized. This study aimed to describe the natural clinical–histopathological trajectory of OLP in a single tertiary centre and to identify factors associated with dysplasia and ...
F. Scilla +8 more
wiley +1 more source
Clinical Equipoise and Unimproved Outcomes following Posttransplant Cutaneous Squamous Cell Carcinoma. [PDF]
Crisp THJ +28 more
europepmc +1 more source
The Role of Viruses in the Pathogenesis of Periodontitis
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte +2 more
wiley +1 more source
Recent Advances in Novel Drug Delivery Systems for the Management of Cutaneous Squamous Cell Carcinoma. [PDF]
Fu X +10 more
europepmc +1 more source
Increased Genetic Instability in Exfoliated Oral Cells in Patients With Epidermolysis Bullosa
ABSTRACT Objective To analyze the nuclear abnormalities of cytotoxicity—karyorrhexis (KR), karyolysis (KL), and pyknosis (PN)—and genotoxicity—micronucleus (MN) in exfoliated cells from different sites of the oral mucosa in patients with Epidermolysis Bullosa (EB) and a control group.
Ana Carolina Sias Franco Franzosi +5 more
wiley +1 more source
Lethal medical course of an untreated giant cutaneous squamous cell carcinoma. [PDF]
Hertzberg J +3 more
europepmc +1 more source
ABSTRACT Objective To synthesize evidence on spirituality in patients with head and neck cancer (HNC), focusing on its dimensions, assessment strategies, and impact on health outcomes. Methods A comprehensive search of PubMed, Embase, LILACS, Web of Science, Scopus, and gray literature identified qualitative and quantitative studies explicitly ...
Liliana Wolf Braun +8 more
wiley +1 more source
EADO classification of difficult-to-treat cutaneous squamous cell carcinoma in transplant recipients. [PDF]
Lara-Trigo J +5 more
europepmc +1 more source

