Results 141 to 150 of about 84,355 (327)

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Extranodal natural killer/T-cell lymphoma with paraneoplastic eosinophilic myositis

Human Pathology: Case Reports, 2020
Extranodal natural killer/T-cell lymphoma is a rare Epstein-Barr virus-associated aggressive lymphoma commonly involving the nasal and upper aerodigestive tract and, less commonly, extranodal sites such as skin and gastrointestinal tract.
Jayati Mallick, Jasmine Zain, Dennis D. Weisenburger   +2 more
doaj  

Childhood primary cutaneous non-T/non-B lymphoma followed by acute T-cell leukemia [PDF]

, 1986
Thomas T. Tang, Stephen J. Lauer, Joseph M. Harb, Phyllis A. Kirchner, Stuart Adair, Bruce M. Camitta   +5 more
openalex   +1 more source

Lymphomatoid Papulosis Following Spesolimab Treatment for Generalised Pustular Psoriasis

Australasian Journal of Dermatology, EarlyView.
Mizuho Namba, Mika Matsumoto, Naoya Saito, Atsuko Kimura, Chihiro Sagara, Daiki Rokunohe, Eijiro Akasaka   +6 more
wiley   +1 more source

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng, Jasper F. Ooms, Erik H. J. Danen, Laura H. Heitman   +3 more
wiley   +1 more source

Lichen Planus Follicularis Tumidus

Australasian Journal of Dermatology, EarlyView.
A. I. Oloruntoba, Saurabh Prakash, Ryan Toholka   +2 more
wiley   +1 more source

Upregulation of YY1/EZH2 and MLH1 as Therapeutic Targets for Adult T‐Cell Leukemia/Lymphoma

Cancer Science, EarlyView.
UMAP projection of CD4 T cells from ATLL patients specified a CD48‐deficient cluster, in which YY1 and EZH2 are upregulated. ABSTRACT The clinical and genetic presentation of adult T‐cell leukemia/lymphoma (ATLL) ranges from indolent to aggressive, making it difficult to identify common therapeutic targets.
Takuya Shimizu, Takero Shindo, Hanako Ogawa, Kaori Teranaka, Akira Watanabe, Akifumi Takaori‐Kondo   +5 more
wiley   +1 more source

Epigenetically‐Upregulated CD98 Shed Light on the Precancerous Diagnosis and Prognosis Prediction of Esophageal Cancer

Cancer Science, EarlyView.
This study confirmed that hypomethylation‐induced upregulation of CD98 promoted ESCC cell proliferation by regulating the cell cycle and was correlated with poorer overall survival of ESCC patients. Combined panels of immunohistochemistry (CD98 and P53) are recommended for accurate diagnosis of esophageal precancerous lesions.
Xue Zhang, Mengfei Sun, Na Li, Jie Yu, Wenjie Wang, Ju Yang, Hongyan Wu, Linyue Zhao, Huakun Zhang, Lan Yang, Feng Li, Qi Sun, Yunzhao Chen, Xiaobin Cui   +13 more
wiley   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

HTLV-I associated cutaneous T-cell lymphoma: report of a case with atypical clinical presentation [PDF]

, 1994
Achiléa Lisbôa Bittencourt, Dilson J. Fernandes, Carlos Sampaio Filho, Edson Duarte Moreira, Terezinha T. Ribeiro, William J. Harrington   +5 more
openalex   +1 more source